Results 231 to 240 of about 7,174,703 (396)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Using generative AI for interview simulations to enhance student research skills in biology education. [PDF]

J Microbiol Biol Educ
Millen JI.
europepmc   +1 more source

Do We Need a New Approach to Cancer Biology Education for Radiation Oncology Residents? [PDF]

Cureus, 2021
Vijayakumar S, King M, Nittala MR, Duhe RJ.   +3 more
europepmc   +1 more source

Virtual Reconstruction and Three-Dimensional Printing of Blood Cells as a Tool in Cell Biology Education

, 2016
Ingrid Augusto, Douglas Alfradique Monteiro, Wendell Girard‐Dias, Thaisa Oliveira dos Santos, Simone Belmonte, Jairo Pinto de Oliveira, Hélder Mauad, Marcos da Silva Pacheco, Dominik Lenz, Athelson Stefanon Bittencourt, Breno Valentim Nogueira, Jorge Roberto Lopes dos Santos, Kildare Miranda, Marco César Cunegundes Guimarães   +13 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Ten simple rules for success as a trainee-led outreach organization in computational biology education. [PDF]

PLoS Comput Biol
Blanc J, Steiner MC, Blake LE, Gibbons E, Ianni-Ravn MK, Morgan RC, Parkinson S, Porras C, Zhong E.   +8 more
europepmc   +1 more source

The effectiveness of the problem-based learning in medical cell biology education: A systematic meta-analysis. [PDF]

Medicine (Baltimore), 2021
Xu W, Ye T, Wang X.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Teachers and Partners are Involved in implementation Project Based Learning Model of Biology Education at SMAN 13 Medan

Nurul Yustiningsih, Virda Kartika Hasibuan, Auliani Putri, Nadia Simanullang, Halim Simatupang, Widya Arwita   +5 more
openalex   +2 more sources