Results 151 to 160 of about 13,793,801 (295)

General Dynamics Corporation Report GA-1612

, 1960
From preface: This report presents the status of design of the MGCR prototype plant as of July 1 ...
General Dynamics Corporation
core  

Author Correction: Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness. [PDF]

Cell Res
Chen J, Qiu S, Li W, Wang K, Zhang Y, Yang H, Liu B, Li G, Li L, Chen M, Lan J, Niu J, He P, Cheng L, Fan G, Liu X, Song X, Xu C, Wu H, Wang H.   +19 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Author Correction: Epigenetic priming of mammalian embryonic enhancer elements coordinates developmental gene networks. [PDF]

Genome Biol
Todd CD, Ijaz J, Torabi F, Dovgusha O, Bevan S, Cracknell O, Lohoff T, Clark S, Argelaguet R, Pearce J, Kafetzopoulos I, Santambrogio A, Nichols J, von Meyenn F, Günesdogan U, Schoenfelder S, Reik W.   +16 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

General Biology Lesson Plans

These biology lesson plans involve spiders, ants, Arizona Hedgehog Cactus, plant collecting, alien plant invasion, unhealthy plants, Drosophila melanogaster, the ecology of the Sonoran Desert soil crusts, diffusion, osmosis and cell membranes, plants and

core  

The WPA Neuropsychiatry Special Interest Group: charting the way forward for neuropsychiatry. [PDF]

World Psychiatry
Sachdev PS.
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Awareness, Attitudes, and Expectations of Indian Cancer Patients and Their Caregivers on Hereditary Cancers and Genetic Testing at a Tertiary Cancer Centre in India. [PDF]

J Genet Couns
Pathak RS, Angre A, Talker J, Sarin R.
europepmc   +1 more source