Results 151 to 160 of about 11,764,337 (376)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Synthetic biology approaches to negative emissions technologies: a technological and ethical appraisal

open access: yesFrontiers in Climate
This article explores the impact that synthetic biology approaches may have on Negative Emissions Technologies (NETs). Synthetic biology has both altered and created biological pathways inspired by nature to develop new NETs that sequester greenhouse ...
Dominic Y. Logel, Josh Wodak
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Soil formation on derivatives of dense rocks of different composition in Transbaikalia

open access: yesБюллетень Почвенного института им. В.В. Докучаева
The soils on the eluvium of dense rocks of different ages, genesis and composition were studied in Transbaikalia. The ecological niches of the soils and their classification position were determined.
A. B. Gyninova   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Sequential and asynchronous processes driven by stochastic or quantum grammars and their application to genomics: a survey

open access: yes, 2005
We present the formalism of sequential and asynchronous processes defined in terms of random or quantum grammars and argue that these processes have relevance in genomics. To make the article accessible to the non-mathematicians, we keep the mathematical
Petritis, Dimitri
core   +1 more source

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