Results 51 to 60 of about 10,999,138 (370)

Tools for Change: Measuring Student Conceptual Understanding Across Undergraduate Biology Programs Using Bio-MAPS Assessments

open access: yesJournal of Microbiology & Biology Education, 2019
Assessing learning across a biology major can help departments monitor achievement of broader program-level goals and identify opportunities for curricular improvement.
Michelle K. Smith   +9 more
doaj   +1 more source

WeNMR : the tale of virtual research community in NMR and structural biology [PDF]

open access: yes, 2013
Structural biology and life sciences in general, and NMR in particular, have always been associated with advanced computing. The current challenges in the post-genomic era call for virtual research platforms that provide the worldwide research community ...
Bonvin, Alexandre   +8 more
core  

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging

open access: yesNature Communications, 2017
Tumour-associated macrophages (TAM) can be used as prognostic indicators in cancer. Here, the authors establish a platform for high-throughput 3D microscopy in murine lung carcinoma that allows to visualize TAMs infiltration throughout the entire lung ...
Michael F. Cuccarese   +7 more
doaj   +1 more source

Why Biology is Beyond Physical Sciences? [PDF]

open access: yes, 2016
In the framework of materialism, the major attention is to find general organizational laws stimulated by physical sciences, ignoring the uniqueness of Life.
Muni, Bhakti Vijnana   +1 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Organismic Supercategories: I. Proposals for a General Unified Theory of Systems- Classical, Quantum, and Complex Biological Systems.\ud \ud \ud [PDF]

open access: yes, 1968
The representation of physical and complex biological systems in terms of organismic supercategories was introduced in 1968 by Baianu and Marinescu in the attached paper which was published in the Bulletin of Mathematical Biophysics, edited by Nicolas ...
Baianu, Prof. Dr. I.C.   +1 more
core  

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens

open access: yesNature Communications, 2018
Diagnostic tests need optimization to avoid invasive and costly repeated biopsies. Here the authors present an antibody-DNA barcoding approach where harvested single cells can be re-stained through custom oligonucleotide-fluorophore conjugates, enabling ...
Randy J. Giedt   +6 more
doaj   +1 more source

The challenges of purely mechanistic models in biology and the minimum need for a 'mechanism-plus-X' framework [PDF]

open access: yes, 2018
Ever since the advent of molecular biology in the 1970s, mechanical models have become the dogma in the field, where a "true" understanding of any subject is equated to a mechanistic description. This has been to the detriment of the biomedical sciences,
Ehsani, Sepehr
core   +1 more source

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