Results 61 to 70 of about 9,085,362 (335)

PROFESSION OF BIOLOGY TEACHER IN UKRAINE: STATISTICAL CHARACTERISTICS

open access: yesНеперервна професійна освіта: теорія та практика
In the context of reforming general secondary education, it is important to identify and analyze the changes occurring in the human resources of the general secondary education system under the influence of various factors, particularly the martial law ...
Lidiia Vashchenko
doaj   +1 more source

Developing a Web-Based Learning (E-Learning) in General Biology Subjects with Joomla Program

open access: yesBiosfer, 2018
Web-based learning has been widely used as learning resources. Developing these learning resources is believed to provide beneficial for students. Therefore, this research was aimed to develop a web-based learning source for General Biology Course.
Muhamad Nurdin Matondang Seribulan   +2 more
doaj   +1 more source

Urban fragmentation leads to lower floral diversity, with knock-on impacts on bee biodiversity

open access: yesScientific Reports, 2020
Bees and flowering plants are two closely interacting groups of organisms. Habitat loss and fragmentation associated with urbanisation are major threats to both partners.
Panagiotis Theodorou   +6 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

General education biology labs: a Delphi study of student learning outcomes

open access: yesDiscover Education
Introductory biology courses at most colleges and universities have two components: a lecture and a lab. However, for students who are not majoring in biology and taking the introductory course as part of their general education requirements, the ...
Dayna Jean DeFeo   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

PRC1 collaborates with SMCHD1 to fold the X-chromosome and spread Xist RNA between chromosome compartments

open access: yesNature Communications, 2019
The inactive X (Xi)-specific S1/S2 chromosome compartments are merged by SMCHD1, but how the S1/S2 structure is constructed is unclear. The authors find that PRC1 drives the formation of S1/S2s and that the stepwise folding process of the Xi facilitates ...
Chen-Yu Wang   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Megadomains and superloops form dynamically but are dispensable for X-chromosome inactivation and gene escape

open access: yesNature Communications, 2018
The mammalian inactive X-chromosome (Xi) is organized into megadomains and superloops directed by the noncoding loci, Dxz4 and Firre. Here the authors provide evidence that megadomains do not precede Xist expression or Xi gene silencing, and suggest that
John E. Froberg   +4 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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