Results 11 to 20 of about 53,084 (170)

Store-Operated Calcium Entry Inhibition and Plasma Membrane Calcium Pump Upregulation Contribute to the Maintenance of Resting Cytosolic Calcium Concentration in A1-like Astrocytes

open access: yesMolecules, 2023
Highly neurotoxic A1-reactive astrocytes have been associated with several human neurodegenerative diseases. Complement protein C3 expression is strongly upregulated in A1 astrocytes, and this protein has been shown to be a specific biomarker of these ...
Joana Poejo   +4 more
doaj   +1 more source

Membrane Lipid Derivatives: Roles of Arachidonic Acid and Its Metabolites in Pancreatic Physiology and Pathophysiology

open access: yesMolecules, 2023
One of the most important constituents of the cell membrane is arachidonic acid. Lipids forming part of the cellular membrane can be metabolized in a variety of cellular types of the body by a family of enzymes termed phospholipases: phospholipase A2 ...
Cándido Ortiz-Placín   +3 more
doaj   +1 more source

Secretion of Interleukin 6 in Human Skeletal Muscle Cultures Depends on Ca2+ Signalling

open access: yesBiology, 2023
The systemic effects of physical activity are mediated by the release of IL-6 and other myokines from contracting muscle. Although the release of IL-6 from muscle has been extensively studied, the information on the cellular mechanisms is fragmentary and
Blanca Calle-Ciborro   +8 more
doaj   +1 more source

Biomarcadores proteicos e infección: ¿Pronóstico de severidad? Revisión Sistemática

open access: yesKasmera, 2021
Los biomarcadores proteicos se relacionan con las infecciones de la vida cotidiana. El uso de éstos permite el diagnóstico y tratamiento temprano, lo cual beneficia al paciente.
Miriam Patricia Razo-Romero   +3 more
doaj   +1 more source

Biomarcadores de riesgo cardio-metabólico-renal: una revisión

open access: yesRevista Colombiana de Endocrinología, Diabetes y Metabolismo, 2023
Contexto: el riesgo cardiovascular confluye con el metabólico y el renal. Objetivo: revisar los biomarcadores moleculares del riesgo cardio-metabólico-renal en Armenia, Quindío. Metodología: una revisión narrativa de los estudios sobre biomarcadores
Olga Alicia Nieto-Cárdenas
doaj   +1 more source

Blood biomarkers in Alzheimer’s disease

open access: yesNeurología (English Edition), 2021
Introduction: Early diagnosis of Alzheimer disease (AD) through the use of biomarkers could assist in the implementation and monitoring of early therapeutic interventions, and has the potential to significantly modify the course of the disease ...
M. Altuna-Azkargorta   +1 more
doaj   +1 more source

Systems Biology Reveals Relevant Gaps in Fc-γR Expression, Impaired Regulatory Cytokine Microenvironment Interfaced With Anti-Trypanosoma cruzi IgG Reactivity in Cardiac Chagas Disease Patients

open access: yesFrontiers in Microbiology, 2018
The systems biology approach has become an innovative tool when it comes to shedding light on the complex immune response underlying the development/maintenance of distinct clinical forms of Chagas disease.
Juliana de A. S. Gomes   +13 more
doaj   +1 more source

Evolution of oxidative stress biomarkers and correlation with competitive performance in two moments of the swimming training season [PDF]

open access: yes, 2009
Estudos têm demonstrado aumento na formação de espécies reativas de oxigênio após o esforço físico intenso. Esses eventos podem aumentar a suscetibilidade das células musculares a danos oxidativos como a peroxidação lipídica.
DEGIOVANNI, Gabriel Carvalho   +5 more
core   +2 more sources

Evaluation of renal function : creatinine and other biomarkers [PDF]

open access: yes, 2007
JUSTIFICATIVA E OBJETIVOS: Os biomarcadores são ferramentas diagnósticas discriminatórias entre o estado de saúde e doença. O objetivo deste estudo foi reconhecer a aplicação clínica dos biomarcadores de função renal na prática clínica, com a finalidade ...
Magro, Márcia Cristina da Silva   +1 more
core   +1 more source

Actualización de las recomendaciones para la determinación de biomarcadores en el carcinoma de pulmón avanzado de célula no pequeña. Consenso Nacional de la Sociedad Española de Anatomía Patológica y de la Sociedad Española de Oncología Médica [PDF]

open access: yes, 2017
En el año 2011 se inició un proyecto conjunto entre la Sociedad Española de Oncología Médica (SEOM) y la Sociedad Española de Anatomía Patológica (SEAP) para establecer unas recomendaciones basadas en la evidencia actual con respecto a la determinación ...
Castro, Javier de   +9 more
core   +1 more source

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