Results 311 to 320 of about 1,688,023 (339)
Some of the next articles are maybe not open access.
2021
Biomarkers have been used in sepsis to assist with the diagnosis of disease as well as determining the severity of disease, that is, prognosis. These biomarkers are based on the presence of discrete molecules within the blood. Unfortunately, in 2020, a single biomarker does not have sufficient sensitivity and specificity to definitively rule in or rule
Yachana, Kataria, Daniel, Remick
openaire +2 more sources
Biomarkers have been used in sepsis to assist with the diagnosis of disease as well as determining the severity of disease, that is, prognosis. These biomarkers are based on the presence of discrete molecules within the blood. Unfortunately, in 2020, a single biomarker does not have sufficient sensitivity and specificity to definitively rule in or rule
Yachana, Kataria, Daniel, Remick
openaire +2 more sources
2015
Biomarkers are key tools and can provide crucial information on the complex cascade of events and molecular mechanisms underlying traumatic brain injury (TBI) pathophysiology. Obtaining a profile of distinct classes of biomarkers reflecting core pathologic mechanisms could enable us to identify and characterize the initial injury and the secondary ...
MONDELLO, STEFANIA, Hayes, Ronald L.
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Biomarkers are key tools and can provide crucial information on the complex cascade of events and molecular mechanisms underlying traumatic brain injury (TBI) pathophysiology. Obtaining a profile of distinct classes of biomarkers reflecting core pathologic mechanisms could enable us to identify and characterize the initial injury and the secondary ...
MONDELLO, STEFANIA, Hayes, Ronald L.
openaire +2 more sources
Chest, 2006
Assessing airway and lung inflammation is important for investigating the underlying mechanisms of asthma and COPD. Yet these cannot be measured directly in clinical research and practice because of the difficulties in monitoring inflammation. Noninvasive monitoring may assist in early recognition of asthma and COPD, assessment of its severity, and ...
Sergei A, Kharitonov, Peter J, Barnes
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Assessing airway and lung inflammation is important for investigating the underlying mechanisms of asthma and COPD. Yet these cannot be measured directly in clinical research and practice because of the difficulties in monitoring inflammation. Noninvasive monitoring may assist in early recognition of asthma and COPD, assessment of its severity, and ...
Sergei A, Kharitonov, Peter J, Barnes
openaire +2 more sources
Drug Testing and Analysis, 2022
AbstractThe concept of biomarker measurements in the form of a ratio has not been explored in detail. This is surprising considering the current and future potential for biomarkers incorporating endogenous reference compounds (ERCs) in a range of fields.
Adam Cawley +4 more
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AbstractThe concept of biomarker measurements in the form of a ratio has not been explored in detail. This is surprising considering the current and future potential for biomarkers incorporating endogenous reference compounds (ERCs) in a range of fields.
Adam Cawley +4 more
openaire +2 more sources
Clinics in Laboratory Medicine, 2012
Excessive alcohol consumption poses a wide variety of significant immediate and long-term health risks. Ethanol biomarkers have clinical utility for detection, diagnosis, and treatment of alcohol use disorders as well as for screening for fetal alcohol exposure. Indirect biomarkers are those that reflect the toxic effects of ethanol on organs, tissues,
openaire +2 more sources
Excessive alcohol consumption poses a wide variety of significant immediate and long-term health risks. Ethanol biomarkers have clinical utility for detection, diagnosis, and treatment of alcohol use disorders as well as for screening for fetal alcohol exposure. Indirect biomarkers are those that reflect the toxic effects of ethanol on organs, tissues,
openaire +2 more sources
Gastroenterology Clinics of North America, 2011
A "biomarker" (biological marker) is an indicator of a bodily function that can be objectively measured. A wide range of possible biomarkers for IBS have been considered but at present only gut transit measured using radio-isotope markers meet the criteria of reproducibility and availability. While barostat studies perform reasonably in expert centers,
openaire +2 more sources
A "biomarker" (biological marker) is an indicator of a bodily function that can be objectively measured. A wide range of possible biomarkers for IBS have been considered but at present only gut transit measured using radio-isotope markers meet the criteria of reproducibility and availability. While barostat studies perform reasonably in expert centers,
openaire +2 more sources
Thrombosis Research, 2012
Cardiovascular diseases (CVD) remain a leading cause of death worldwide. In the past years new biomarkers have drawn the clinician's attention for their use in primary prevention and in the identification of individuals at cardiovascular risk. Biomarkers also provide information on the progression and possible recurrence of cardiovascular events, and ...
L, Badimon +3 more
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Cardiovascular diseases (CVD) remain a leading cause of death worldwide. In the past years new biomarkers have drawn the clinician's attention for their use in primary prevention and in the identification of individuals at cardiovascular risk. Biomarkers also provide information on the progression and possible recurrence of cardiovascular events, and ...
L, Badimon +3 more
openaire +2 more sources
2010
Profound changes in the epigenetic landscape of cancer cells underlie the development of human malignancies. These changes include large-scale DNA methylation changes throughout the genome as well as alterations in the compendium of post-translational chromatin modifications. Epigenetic aberrations impact multiple steps during tumorigenesis, ultimately
Timothy A, Chan, Stephen B, Baylin
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Profound changes in the epigenetic landscape of cancer cells underlie the development of human malignancies. These changes include large-scale DNA methylation changes throughout the genome as well as alterations in the compendium of post-translational chromatin modifications. Epigenetic aberrations impact multiple steps during tumorigenesis, ultimately
Timothy A, Chan, Stephen B, Baylin
openaire +2 more sources