Results 221 to 230 of about 4,189,421 (356)

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Early and hereditary breast cancer: advances in risk stratification and imaging approaches. [PDF]

Ther Adv Med Oncol
Cortiana V, Kannan S, Vallabhaneni H, Gambill J, Nadar S, Jigar Kumar Rangrej V, Park CH, Leyfman Y.   +7 more
europepmc   +1 more source

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.

Cancer Discovery, 2016
Pei-Ling Chen, Whijae Roh, A. Reuben, Z. Cooper, C. Spencer, P. Prieto, John P Miller, R. Bassett, V. Gopalakrishnan, K. Wani, M. P. de Macedo, J. Austin-Breneman, Hong Jiang, Q. Chang, S. Reddy, Wei-Shen Chen, M. Tetzlaff, R. Broaddus, M. Davies, J. Gershenwald, L. Haydu, A. Lazar, S. Patel, P. Hwu, W. Hwu, A. Diab, I. Glitza, S. Woodman, L. Vence, I. Wistuba, R. Amaria, L. Kwong, V. Prieto, R. Davis, Wencai Ma, W. Overwijk, A. Sharpe, Jianhua Hu, P. Futreal, J. Blando, Padmanee Sharma, J. Allison, L. Chin, J. Wargo   +43 more
semanticscholar   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

A Comprehensive Oncological Biomarker Framework Guiding Precision Medicine. [PDF]

Biomolecules
Mokhtari RB, Sambi M, Shekari F, Satari K, Ghafoury R, Ashayeri N, Eversole P, Baluch N, Harless WW, Muscarella LA, Yeger H, Das B, Szewczuk MR, Chakraborty S.   +13 more
europepmc   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

Integrating the secretome and interactome to identify novel biomarkers and therapeutic targets in colorectal cancer. [PDF]

Cell Commun Signal
Caxali GH, Aal MCE, Osvaldo CWG, Oliveira JS, Bidinotto LT, Carvalho RF, Delella FK.   +6 more
europepmc   +1 more source

Adipokines and Associations with Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Purpose We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker, Bryant R. England, Michael D. George, Hannah Brubeck, Brian Sauer, Aleksander Lenert, Punyasha Roul, Geoffrey M. Thiele, Ted R. Mikuls, Katherine D. Wysham   +9 more
wiley   +1 more source

Exploration of propionate metabolism-related genes to predict prognosis and immunotherapy response in ovarian cancer. [PDF]

J Ovarian Res
Ni J, Qiu J, Ma Y.
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source