Results 81 to 90 of about 4,176,355 (337)

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

MicroRNAs As Biomarkers of Brain Tumors

Cancer Management and Research
Brain tumors still remain a deadly cancer that, in most cases, is difficult to diagnose at an earlier stage. Therefore, it is necessary to develop rapid, sensitive methods for detecting cancer biomarkers. Such a biomarker may be a microRNA which expression level in body fluids is strongly correlated with cancer.
Jelski W, Mroczko B
openaire   +4 more sources

Biomarkers of Pineal Region Tumors: A Review [PDF]

Ochsner Journal, 2019
Background: The pineal gland, a small, pinecone-shaped organ deep within the brain, is responsible for producing melatonin. The gland consists of pineal parenchymal cells and glial cells that can form neoplasms. Pineal region neoplasms can also arise from germ cells and adjacent structures.
Carr, Christopher, O'Neill, Brannan E., Hochhalter, Christian B., Strong, Michael J., Ware, Marcus L.   +4 more
openaire   +3 more sources

Amygdalin as a chemoprotective agent in co-treatment with cisplatin

Frontiers in Pharmacology, 2022
Amygdalin is a naturally occurring glycoside used in traditional Chinese medicine and is known to have anti-cancer properties. Even though the anti-cancer properties of amygdalin are well known, its effect on normal cells has not been thoroughly ...
Panayiota Christodoulou, Panayiota Christodoulou, Panagiotis Boutsikos, Christiana M. Neophytou, Theodora-Christina Kyriakou, Theodora-Christina Kyriakou, Maria-Ioanna Christodoulou, Panagiotis Papageorgis, Anastasis Stephanou, Ioannis Patrikios   +9 more
doaj   +1 more source

A coordinate deregulation of microRNAs expressed in mucosa adjacent to tumor predicts relapse after resection in localized colon cancer [PDF]

, 2018
Up to 20% of colorectal cancer (CRC) node-negative patients develop loco-regional or distant recurrences within 5 years from surgery. No predictive biomarker able to identify the node-negative subjects at high risk of relapse after curative treatment is ...
Albertoni, Laura, Fassan, Matteo, Grassi, Angela, Mescoli, Claudia, Perilli, Lisa, Rugge, Massimo, Tessarollo, Sofia, Urso, Emanuele D. L., Zanovello, Paola   +8 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Characterization of Cognitive Function in Survivors of Diffuse Gliomas Using Morphometric Correlation Networks

Tomography, 2022
This pilot study investigates structural alterations and their relationships with cognitive function in survivors of diffuse gliomas. Twenty-four survivors of diffuse gliomas (mean age 44.5 ± 11.5), from whom high-resolution T1-weighted images ...
Chencai Wang, Nicholas S. Cho, Kathleen Van Dyk, Sabah Islam, Catalina Raymond, Justin Choi, Noriko Salamon, Whitney B. Pope, Albert Lai, Timothy F. Cloughesy, Phioanh L. Nghiemphu, Benjamin M. Ellingson   +11 more
doaj   +1 more source

A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]

, 2015
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W, Faltermeier, Claire, Zarrinpar, Ali   +2 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Survival differences between women and men in the non-reproductive cancers: Results from a matched analysis of the surveillance, epidemiology, and end-results program

Frontiers in Public Health, 2023
BackgroundMen with non-reproductive cancers have a discrepant outcome compared to women. However, they differ significantly in the incidence of cancer type and characteristics.MethodsPatients with single primary cancer who were 18 years or older and ...
Felipe Andrés Cordero da Luz, Felipe Andrés Cordero da Luz, Camila Piqui Nascimento, Eduarda da Costa Marinho, Pollyana Júnia Felicidade, Rafael Mathias Antonioli, Rogério Agenor de Araújo, Rogério Agenor de Araújo, Rogério Agenor de Araújo, Marcelo José Barbosa Silva   +9 more
doaj   +1 more source