Results 101 to 110 of about 2,936,789 (384)
Journal for ImmunoTherapy of CancerBackground In patients with locally advanced unresectable non-small cell lung cancer (NSCLC), durvalumab, an anti-programmed cell death ligand-1 (PD-L1) antibody, has shown improved overall survival when used as consolidation therapy following concurrent
Tanja D de Gruijl +13 more
doaj +1 more source
Scientific Reports, 2017 There is conflicting evidence on the favorable effects of vitamin D supplementation on metabolic profile in Type 2 diabetes mellitus (T2DM) patients and this might be due to genetic variations in vitamin D receptors (VDRs). Thus, we studied the metabolic
Nasser M. Al-Daghri +8 more
doaj +1 more source
Characterization of retinal function and structure in the MPTP murine model of Parkinson’s disease
Scientific Reports, 2022 In addition to well characterized motor symptoms, visual disturbances are increasingly recognized as an early manifestation in Parkinson’s disease (PD). A better understanding of the mechanisms underlying these changes would facilitate the development of
Katie K. N. Tran +7 more
doaj +1 more source
Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases [PDF]
, 2016 Purpose of review: Urine is the most useful of body fluids for biomarker research. Therefore, we have focused on urinary proteomics, using capillary electrophoresis coupled to mass spectrometry, to investigate kidney diseases in recent years.
Magalhães, Pedro +2 more
core +1 more source
Cancer Stem Cells—Origins and Biomarkers: Perspectives for Targeted Personalized Therapies
Frontiers in Immunology, 2020 The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest over the last decades. In particular, the analysis of biomarkers in cancer patients within the pre- and post-therapeutic period is required to identify several types
Lia Walcher +9 more
semanticscholar +1 more source
Journal of Korean Neurosurgical Society, 2015 Moyamoya disease (MMD) is an arteriopathy of the intracranial circulation predominantly affecting the branches of the internal carotid arteries. Heterogeneity in presentation, progression and response to therapy has prompted intense study to improve the diagnosis and prognosis of this disease.
openaire +3 more sources
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
OncoImmunology, 2017 Although promising, the clinical benefit provided by dendritic cell (DC)-based vaccines is still limited and the choice of the optimal antigen formulation is still an unresolved issue.
B. Montico +16 more
doaj +1 more source
Serum Metabolic Alterations upon Zika Infection
Frontiers in Microbiology, 2017 Zika virus (ZIKV) infection has recently emerged as a major concern worldwide due to its strong association with nervous system malformation (microcephaly) of fetuses in pregnant women infected by the virus. Signs and symptoms of ZIKV infection are often
Carlos Fernando O. R. Melo +44 more
doaj +1 more source
A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]
, 2017 Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M. +17 more
core +2 more sources