Results 171 to 180 of about 2,058,753 (356)

Biomarkers in the detection of human heritable and germinal mutagenesis.

, 1987
M.L. Mendelsohn
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS[S]

Journal of Lipid Research, 2011
High resolution LC/MS-MS and LC/APPI-MS methods have been established for the quantitation of flux in the turnover of cholesterol and cholesterol ester.
Jose Castro-Perez, Stephen F. Previs, David G. McLaren, Vinit Shah, Kithsiri Herath, Gowri Bhat, Douglas G. Johns, Sheng-Ping Wang, Lyndon Mitnaul, Kristian Jensen, Robert Vreeken, Thomas Hankemeier, Thomas P. Roddy, Brian K. Hubbard   +13 more
doaj  

Somatic cell gene mutations in humans: biomarkers for genotoxicity.

, 1993
R.J. Albertini, Janice A. Nicklas, John P. O’Neill   +2 more
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Use and misuse of biomarker tests in “environmental conditions” [PDF]

, 1994
John E. Salvaggio
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

The effect of drying methods on bioactive properties in three varieties of prickly pear (Opuntia ficus indica)

Journal of Nutrition & Intermediary Metabolism, 2017
C.A. Gouws, N. D’Cunha, E. Georgousopoulou, J. Thomas, D.D. Mellor, P.D. Roach, N. Naumovski   +6 more
doaj   +1 more source

Biomarkers in epidemiology: scientific issues and ethical implications.

, 1992
Paul A. Schulte
openalex   +1 more source

DNA adducts as biomarkers for assessing exposure to polycyclic aromatic hydrocarbons in tissues from Xuan Wei women with high exposure to coal combustion emissions and high lung cancer mortality [PDF]

, 1994

openalex   +1 more source