Results 171 to 180 of about 2,244,220 (290)

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Bacteriohopanepolyol biomarkers of sediments from the Congo fan

, 2008
Martin P. Cooke, Helen M. Talbot, Thomas Wagner   +2 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Neurophysiological, Radiological, and Molecular Biomarkers of Pain-Related Conditions: An Umbrella Review. [PDF]

J Clin Med
Viderman D, Kalikanov S, Mukazhan D, Nurmukhamed B.   +3 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Clinical translation of fluid, imaging, and digital biomarkers for Alzheimer's disease. [PDF]

Alzheimers Res Ther
Bacci JR, Karagianni S, Alexopoulou ZS, Moukaled S, Tato-Fernández C, Arunachalam P, Aslanyan A, Aye S, Rocha ASL, Crugel M, Fawad A, Sogorb-Esteve A, Schöll M, König A, Paterson RW.   +14 more
europepmc   +1 more source

Correction: Extracellular matrix remodeling proteins as biomarkers for clinical assessment and treatment outcomes in eosinophilic esophagitis

BMC Gastroenterology, 2023
Martin Pehrsson, Willemijn E. de Rooij, Anne-Christine Bay-Jensen, Morten Asser Karsdal, Joachim Høg Mortensen, Albert Jan Bredenoord   +5 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Sepsis Prediction: Biomarkers Combined in a Bayesian Approach [PDF]

João Victor Batista Cabral, Maria Mariana Barros Melo da Silveira, Amanda Tavares Xavier, Fábio Henrique Portella Corrêa de Oliveira, Thaysa Maria Gama Leao de Albuquerque MENEZES, Keylla Talitha Fernandes Barbosa, Thaisa Remigio Figueirêdo, Jabiael Carneiro da Silva Filho, T A M A R A Silva, Dário Celestino Sobral Filho, Dinaldo Cavalcanti de Oliveira   +10 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source