Results 221 to 230 of about 1,859,513 (388)

Molecular Epidemiology of Aflatoxin Exposures: Validation of Aflatoxin-N7-Guanine Levels in Urine As a Biomarker in Experimental Rat Models and Humans

, 1993
John D. Groopman, Christopher P. Wild, Julia A. Hasler, Chen Junshi, Gerald N. Wogan, Thomas W. Kensler   +5 more
openalex   +1 more source

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

FEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla, Faiza Abbas, Luigia Rossi, Mauro Magnani, Sara Biagiotti   +4 more
wiley   +1 more source

Explainable machine learning framework for biomarker discovery by combining biological age and frailty prediction. [PDF]

Sci Rep
Wang X, Ji J.
europepmc   +1 more source

Application of molecular biomarkers in epidemiology.

, 1994
Martyn T. Smith, William A. Suk
openalex   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Identification and enrichment of potential pathways in the buffy coat of patients with DRE using non-targeted metabolomics integrated with GEO Datasets. [PDF]

Eur J Med Res
Zhu H, Zheng S, Xie L, Yun Y, Kwan P, Rollo B, Huang H.   +6 more
europepmc   +1 more source

Conceptual strategy for design, implementation, and validation of a biomarker-based biomonitoring capability

, 1991
John F. McCarthy, Richard S. Halbrook, L.R. Shugart   +2 more
openalex   +2 more sources

Age-Dependent Accumulation of Dolichol in Rat Liver: Is Tissue Dolichol a Biomarker of Aging? [PDF]

, 1998
Maria Marino, C Dolfi, C. Paradiso, Gabriella Cavallini, Matilde Masini, Z. Gori, M. Pollera, A. Trentalance, E. Bergamini   +8 more
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

The role and clinical significance of myeloperoxidase (MPO) and TNF-α in prognostic evaluation of T-COPD. [PDF]

BMC Pulm Med
Jiang E, Fu Y, Wang Y, Ying L, Li W.
europepmc   +1 more source