Results 231 to 240 of about 2,244,220 (290)

The Knowledge Connector decision support system for multiomics-based precision oncology. [PDF]

Nat Commun
Hübschmann D, Kreutzfeldt S, Roth B, Glocker K, Schoop J, Oeser L, Hausmann S, Koch C, Uhrig S, Hüllein J, Hutter B, Fröhlich M, Heilig CE, Teleanu MV, Lipka DB, Kerle IA, Baude-Müller A, Beck K, Heining C, Glimm H, Ückert F, Knurr A, Fröhling S, Horak P.   +23 more
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Identification and Verification of Biomarkers Related to Polyamine Metabolism in Diabetic Nephropathy. [PDF]

J Diabetes Res
Zhou S, An H, Wei H, Wu R, Wang Z, Liu M, Liu T, Li K.   +7 more
europepmc   +1 more source

Evaluation of a serum protein signature as monitoring biomarker for Duchenne Muscular Dystrophy in a long-term clinical trial with corticosteroids [PDF]

C. Degan, Rebecca Tobin, Sharon de Vries, Albert Jiménez-Requena, Amela Peco, Michela Guglieri, Jordi Diaz-Manera, Y. Van Der Burgt, Bart J. M. Vlijmen, FOR-DMD investigators of the Muscle Study Group, Yetrib Hathout, Cristina Al-Khalili Szigyarto, Utkarsh J. Dang, Roula Tsonaka, Pietro Spitali   +14 more
openalex   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Academic stress through salivary biomarkers: A multivariate exploration of cortisol, IL-1β, CRP, and IgA levels with sex-specific insights. [PDF]

PLoS One
Castillo-Klagges R, Pezo-Sáez C, Aguila L, Pantoja V, Treulen F.   +4 more
europepmc   +1 more source

Proteomic Profiling of Human Synovial Fluid Reveals AKR1C1 as a Biomarker of Osteoarthritis Severity

Patricia Fernández‐Puente, Rocío Paz-González, V. Calamia, F. Picchi, Patricia Quaranta, L. Lourido, Selva Riva-Mendoza, Martin Lotz, Francisco J. Blanco, Cristina Ruíz‐Romero   +9 more
openalex   +2 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Comprehensive Landscape of Diagnostic, Prognostic and Predictive Biomarkers in Colorectal Cancer: From Genomics to Multi-Omics Integration in Precision Medicine. [PDF]

J Pers Med
Agüera-Sánchez A, Peña-Ros E, Martínez-Martínez I, García-Molina F.   +3 more
europepmc   +1 more source