Results 321 to 330 of about 2,145,918 (335)
Some of the next articles are maybe not open access.
Biomarkers: to be or not to be
Annals of the Rheumatic Diseases, 2020We read with great interest the article by van den Hoogen et al 1 describing galectin-9 (Gal-9) as a novel, easy-to-measure biomarker for the interferon (IFN) signature in systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). We support the views expressed by the authors that IFN signature is an important biomarker in disease activity
Lars Rönnblom, Sule Yavuz
openaire +3 more sources
2015
Biomarkers are key tools and can provide crucial information on the complex cascade of events and molecular mechanisms underlying traumatic brain injury (TBI) pathophysiology. Obtaining a profile of distinct classes of biomarkers reflecting core pathologic mechanisms could enable us to identify and characterize the initial injury and the secondary ...
MONDELLO, STEFANIA, Hayes, Ronald L.
openaire +3 more sources
Biomarkers are key tools and can provide crucial information on the complex cascade of events and molecular mechanisms underlying traumatic brain injury (TBI) pathophysiology. Obtaining a profile of distinct classes of biomarkers reflecting core pathologic mechanisms could enable us to identify and characterize the initial injury and the secondary ...
MONDELLO, STEFANIA, Hayes, Ronald L.
openaire +3 more sources
2019
Aggressive behavior exerts an enormous impact on society remaining among the main causes of worldwide premature death. Effective primary interventions, relying on predictive models of aggression that show adequate sensitivity and specificity are currently lacking.
Vassilios Fanos +8 more
openaire +3 more sources
Aggressive behavior exerts an enormous impact on society remaining among the main causes of worldwide premature death. Effective primary interventions, relying on predictive models of aggression that show adequate sensitivity and specificity are currently lacking.
Vassilios Fanos +8 more
openaire +3 more sources
Current Opinion in Organ Transplantation, 2013
As the induction and maintenance of donor-specific tolerance is a central aim in solid organ transplantation, it is essential that clinicians are able to identify and monitor tolerance accurately and reliably. This review highlights recent advances in defining sets of biomarkers in noninvasive samples that may guide minimization and withdrawal of ...
Gökmen, Refik, Hernandez Fuentes, Maria
openaire +3 more sources
As the induction and maintenance of donor-specific tolerance is a central aim in solid organ transplantation, it is essential that clinicians are able to identify and monitor tolerance accurately and reliably. This review highlights recent advances in defining sets of biomarkers in noninvasive samples that may guide minimization and withdrawal of ...
Gökmen, Refik, Hernandez Fuentes, Maria
openaire +3 more sources
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 1988
Abstract This article presents a conceptual discussion of some aspects involved in biomarkers in aging. A biomarker of aging is a biological parameter of an organism that either alone or in some multivariate composite will, in the absence of disease, better predict functional capability at some late age than will chronological age.
openaire +5 more sources
Abstract This article presents a conceptual discussion of some aspects involved in biomarkers in aging. A biomarker of aging is a biological parameter of an organism that either alone or in some multivariate composite will, in the absence of disease, better predict functional capability at some late age than will chronological age.
openaire +5 more sources
2000
Earthworms are believed to be so-called key species within ecosystems and are often exposed to a wide range of anthropogenic compounds released to the terrestrial environment. As a consequence, they may suffer from the toxicity of these compounds. For these and other reasons, earthworms have been used extensively in ecotoxicological studies.
Scott-Fordsmand, J. J., Weeks, J. M.
openaire +3 more sources
Earthworms are believed to be so-called key species within ecosystems and are often exposed to a wide range of anthropogenic compounds released to the terrestrial environment. As a consequence, they may suffer from the toxicity of these compounds. For these and other reasons, earthworms have been used extensively in ecotoxicological studies.
Scott-Fordsmand, J. J., Weeks, J. M.
openaire +3 more sources
Biomarkers in pediatrics: Children as biomarker orphans
PROTEOMICS – Clinical Applications, 2010AbstractBiomarkers have enormous potential to improve patient care by establishing tests of diagnosis, prognosis, and treatment effects. Successfully translating a biomarker from discovery to clinical application demands high‐quality discovery research and high‐quality clinical studies for biomarker validation; however, there are additional challenges ...
Allen D. Everett, William J. Savage
openaire +3 more sources
Pulmonary Pharmacology & Therapeutics, 2010
Although there is increasing interest in using pulmonary biomarkers for a more complete and clinically relevant assessment of COPD and a plethora of biomarkers are becoming available, there is little information regarding their reproducibility and correlation with other outcome measurements in COPD.
CAZZOLA, MARIO, NOVELLI, GIUSEPPE
openaire +4 more sources
Although there is increasing interest in using pulmonary biomarkers for a more complete and clinically relevant assessment of COPD and a plethora of biomarkers are becoming available, there is little information regarding their reproducibility and correlation with other outcome measurements in COPD.
CAZZOLA, MARIO, NOVELLI, GIUSEPPE
openaire +4 more sources
Scandinavian Journal of Clinical and Laboratory Investigation, 2016
Malignant melanoma remains the skin cancer with the highest number of mortalities worldwide. While early diagnosis and complete surgical excision remain the best possibility for curing disease, prognosis at the stage of metastasis is still poor. Recent years have brought about considerable advances in terms of understanding the pathogenesis of melanoma
openaire +3 more sources
Malignant melanoma remains the skin cancer with the highest number of mortalities worldwide. While early diagnosis and complete surgical excision remain the best possibility for curing disease, prognosis at the stage of metastasis is still poor. Recent years have brought about considerable advances in terms of understanding the pathogenesis of melanoma
openaire +3 more sources