Vascular-related biological stress, DNA methylation, allostatic load and domain-specific cognition: an integrated machine learning and causal inference approach. [PDF]
Waziry R+3 more
europepmc +1 more source
The Case of a 67‐Year‐Old Man With Memory Difficulties and Altered Sleep
Annals of Clinical and Translational Neurology, EarlyView.
Wesley Peng, Borna Bonakdarpour
wiley +1 more source
CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus
ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh+8 more
wiley +1 more source
Changing definitions of disease: Transformations in the diagnostic criteria for Alzheimer's disease. [PDF]
van der Molen LH+3 more
europepmc +1 more source
Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy
ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling+6 more
wiley +1 more source
Mediators of Filgotinib Treatment Effects in Ulcerative Colitis: Exploring Circulating Biomarkers in the Phase 2b/3 SELECTION Study. [PDF]
Nakase H+15 more
europepmc +1 more source
ABSTRACT Objective Quantitative markers of cortical excitability may help identify responders to anti‐seizure medications (ASMs). We studied the relationship between ASM load and two electroencephalography (EEG) markers of cortical excitability in people with refractory epilepsy. Methods We included individuals with refractory focal epilepsy undergoing
Silvano R. Gefferie+7 more
wiley +1 more source
A thematic analysis of prognostic, diagnostic, and therapeutic of circulating miRNA biomarkers in bortezomib-resistant multiple myeloma. [PDF]
Bamfield-Cummings S, Silva J, Karim ZA.
europepmc +1 more source
ABSTRACT Objective To investigate the reliability of very high‐frequency oscillations (VHFOs, 500–2000 Hz) as biomarkers in identifying the epileptogenic zone (EZ) in mesial temporal lobe epilepsy (MTLE) patients. Methods We reviewed 19 MTLE patients who underwent stereo‐electroencephalography‐guided radiofrequency thermocoagulation.
Stéphane Jean+10 more
wiley +1 more source
Biomarkers for SARS-CoV-2 infection. A narrative review. [PDF]
Snopkowska Lesniak SW+3 more
europepmc +1 more source