Results 21 to 30 of about 72,568 (267)
Antioxidants, 2020 Lindera obtusiloba is widespread in northeast Asia and used for treatment of improvement of blood circulation and anti-inflammation. In this study, we investigated anti-inflammatory and anti-oxidant effects of the methanolic extract of L.
Ba-Wool Lee +12 more
doaj +1 more source
A Quantitative Structure-Activity Relationship for Human Plasma Protein Binding: Prediction, Validation and Applicability Domain [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: The purpose of this study was to develop a robust and externally predictive in silico QSAR-neural network model for predicting plasma protein binding of drugs. This model aims to enhance drug discovery processes by reducing the need for chemical
Affaf Khaouane +2 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Alnus hirsuta (Spach) Rupr. (AH), a member of the Betulaceae family, is widely used in Eastern Asia of as a source of medicinal compounds for the treatment of hemorrhage, diarrhea, and alcoholism.
Ba-Wool Lee +13 more
doaj +1 more source
Application of Chitosan-Liquid Smoke Nanocoating to Extend the Shelf Life of Fresh Tuna Fillets
Computational and Experimental Research in Materials and Renewable EnergyThe present study aimed to investigate the effectiveness of chitosan nano-sized particles combined with liquid smoke in extending the shelf life while maintaining the quality of tuna fish fillets during 15 days of cold storage.
Bambang Piluharto +4 more
doaj +1 more source
Journal of Immunology Research, 2018 Tumor is the most serious threat to human beings. Although war against cancer has been launched over forty years, cancer treatment is still far away from being satisfactory.
Huan Zhao +3 more
doaj +1 more source
Advanced Healthcare Materials, 2020 AbstractSince their initial description in 2005, biomaterials that are patterned to contain microfluidic networks (“microfluidic biomaterials”) have emerged as promising scaffolds for a variety of tissue engineering and related applications. This class of materials is characterized by the ability to be readily perfused.
Joe Tien, Yoseph W. Dance
openaire +3 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Sleep Apnea Severity Estimation From Tracheal Movements Using a Deep Learning Model
IEEE Access, 2020 Objective: Sleep apnea is a chronic respiratory disorder and its standard assessment requires full night in-laboratory polysomnography (PSG). However, PSG is expensive, time-consuming, and inconvenient.
Maziar Hafezi +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source