Results 41 to 50 of about 169,317 (306)

Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. [PDF]

, 2018
Injectable hydrogels with tunable physiochemical and biological properties are potential tools for improving neural stem/progenitor cell (NSPC) transplantation to treat central nervous system (CNS) injury and disease.
Czechanski, A, Deming, TJ, Kim, JH, O'Shea, TM, Reinholdt, LG, Sofroniew, MV, Wollenberg, AL   +6 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Sleep Apnea Severity Estimation From Tracheal Movements Using a Deep Learning Model

IEEE Access, 2020
Objective: Sleep apnea is a chronic respiratory disorder and its standard assessment requires full night in-laboratory polysomnography (PSG). However, PSG is expensive, time-consuming, and inconvenient.
Maziar Hafezi, Nasim Montazeri, Shumit Saha, Kaiyin Zhu, Bojan Gavrilovic, Azadeh Yadollahi, Babak Taati   +6 more
doaj   +1 more source

Escherichia coli Biofilm Formation, Motion and Protein Patterns on Hyaluronic Acid and Polydimethylsiloxane Depend on Surface Stiffness

Journal of Functional Biomaterials, 2022
The surface stiffness of the microenvironment is a mechanical signal regulating biofilm growth without the risks associated with the use of bioactive agents.
Annabelle Vigué, Dominique Vautier, Amad Kaytoue, Bernard Senger, Youri Arntz, Vincent Ball, Amine Ben Mlouka, Varvara Gribova, Samar Hajjar-Garreau, Julie Hardouin, Thierry Jouenne, Philippe Lavalle, Lydie Ploux   +12 more
doaj   +1 more source

Enzymatic activity toward poly(L-lactic acid) implants [PDF]

, 1990
Tissue reactions toward biodegradable poly(L-lactic acid) implants were monitored by studying the activity pattern of seven enzymes as a function of time: alkaline phosphatase, acid phosphatase, -naphthyl acetyl esterase, -glucuronidase, ATP-ase, NADH ...
Feijen, J., Hardonk, M.J., Molenaar, I., Nieuwenhuis, P., Schakenraad, J.M.   +4 more
core   +4 more sources

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes

Bioengineering, 2023
Induced pluripotent stem cells (iPSCs) have become a prevalent topic after their discovery, advertised as an ethical alternative to embryonic stem cells (ESCs).
Fuga Takahashi, Praneel Patel, Takahiro Kitsuka, Kenichi Arai   +3 more
doaj   +1 more source

Foreign body responses in central nervous system mimic natural wound responses and alter biomaterial functions [PDF]

, 2019
Biomaterials hold promise for diverse therapeutic applications in the central nervous system (CNS). Little is known about molecular factors that determine CNS foreign body responses (FBRs) in vivo , or about how such responses influence biomaterial ...
Ao, Yan, Deming, Timothy, Kim, Jae, O’Shea, Timothy, Sofroniew, Michael, Wollenberg, Alexander   +5 more
core   +1 more source

The use of a non-absorbable membrane as an occlusive barrier for alveolar ridge preservation: A one year follow-up prospective cohort study [PDF]

, 2020
The aims of this study were to obtain preliminary data and test the clinical efficacy of a novel nonporous dense-polytetrafluoroethylene (d-PTFE) membrane (permamem®, botiss) in alveolar ridge preservation (ARP) procedures with a flapless approach.
D'addona, A., Di Murro, B., Papi, P., Passarelli, P. C., Pompa, G., Tromba, M.   +5 more
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source