Results 71 to 80 of about 307,580 (386)

The Application of Nanoparticle-Based Drug Delivery Systems in Checkpoint Blockade Cancer Immunotherapy

open access: yesJournal of Immunology Research, 2018
Tumor is the most serious threat to human beings. Although war against cancer has been launched over forty years, cancer treatment is still far away from being satisfactory.
Huan Zhao   +3 more
doaj   +1 more source

Effects of Vigna angularis extract and its active compound hemiphloin against atopic dermatitis-like skin inflammation

open access: yesHeliyon, 2023
Vigna angularis is an edible crop and herbal medicine that is known to have antipyretic, anti-inflammatory, and anti-edema effects. Many studies have been conducted on the 95% ethanol extract of V.
Seon Gyeong Bak   +8 more
doaj   +1 more source

Ontology-based knowledge representation of experiment metadata in biological data mining [PDF]

open access: yes, 2009
According to the PubMed resource from the U.S. National Library of Medicine, over 750,000 scientific articles have been published in the ~5000 biomedical journals worldwide in the year 2007 alone.
Burke, Squires   +12 more
core   +1 more source

A Review on Chitosan’s Uses as Biomaterial: Tissue Engineering, Drug Delivery Systems and Cancer Treatment

open access: yesMaterials, 2020
Chitosan, derived from chitin, is a biopolymer consisting of arbitrarily distributed β-(1-4)-linked D-glucosamine and N-acetyl-D-glucosamine that exhibits outstanding properties— biocompatibility, biodegradability, non-toxicity, antibacterial activity ...
Rayssa de Sousa Victor   +5 more
semanticscholar   +1 more source

Escherichia coli Biofilm Formation, Motion and Protein Patterns on Hyaluronic Acid and Polydimethylsiloxane Depend on Surface Stiffness

open access: yesJournal of Functional Biomaterials, 2022
The surface stiffness of the microenvironment is a mechanical signal regulating biofilm growth without the risks associated with the use of bioactive agents.
Annabelle Vigué   +12 more
doaj   +1 more source

Acrylamide Production Using Encapsulated Nitrile Hydratase from \u3cem\u3ePseudonocardia thermophila\u3c/em\u3e in a Sol–gel Matrix [PDF]

open access: yes, 2014
The cobalt-type nitrile hydratase from Pseudonocardia thermophila JCM 3095 (PtNHase) was successfully encapsulated in tetramethyl orthosilicate sol–gel matrices to produce a PtNHase:sol–gel biomaterial.
Elgren, Timothy E.   +4 more
core   +1 more source

Multi-function based modeling of 3D heterogeneous wound scaffolds for improved wound healing [PDF]

open access: yes, 2010
This paper presents a new multi-function based modeling of 3D heterogeneous porous wound scaffolds to improve wound healing process for complex deep acute or chronic wounds.
Koc, Bahattin   +3 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

A Novel Methodology for Human Plasma Protein Binding: Prediction, Validation, and Applicability Domain

open access: yesPharmaceutical and Biomedical Research, 2022
Background: Plasma protein binding is a key component in drug therapy as it affects the pharmacokinetics and pharmacodynamics of drugs. Objectives: This study aimed to predict the fraction of plasma protein binding.
Affaf Khaouane   +2 more
doaj  

The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes

open access: yesBioengineering, 2023
Induced pluripotent stem cells (iPSCs) have become a prevalent topic after their discovery, advertised as an ethical alternative to embryonic stem cells (ESCs).
Fuga Takahashi   +3 more
doaj   +1 more source

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