Results 81 to 90 of about 100,486 (293)

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

open access: yesAdvanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang   +16 more
wiley   +1 more source

Deep Learning-Based Drug Half-Life Classification to Enhance Drug Development and Pharmacokinetics [PDF]

open access: yesAdvanced Pharmaceutical Bulletin
Purpose: Predicting drug half-life is essential in pharmacokinetics (PK), influencing dosing strategies and guiding drug development. Traditional regression models estimate exact half-life values but are sensitive to pharmacokinetic variability, limiting
Affaf Khaouane   +2 more
doaj   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

open access: yesAdvanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran   +11 more
wiley   +1 more source

Ketahanan Papan Komposit dari Pelepah Sagu (Metroxylon sago Rottb.) terhadap Jamur Pelapuk dan Rayap Tanah

open access: yesJurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2014
Penelitian ini bertujuan untuk menguji ketahanan papan komposit dari pelepah sagu menggunakan perekat polyurethane (PU)dan phenol formaldehyde (PF) terhadap jamur pelapuk dan rayap.
Deni Zulfiana, Sukma S Kusumah
doaj   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Isolation and Characterization of the Colletotrichum acutatum ABC Transporter CaABC1

open access: yesThe Plant Pathology Journal, 2014
Fungi tolerate exposure to various abiotic stresses, including cytotoxic compounds and fungicides, via their ATP-driven efflux pumps belonging to ATP-binding cassette (ABC) transporters.
Suyoung Kim   +7 more
doaj   +1 more source

Additively Manufactured Diamond for Energy Scavenging and Wireless Power Transfer in Implantable Devices

open access: yesAdvanced Functional Materials, EarlyView.
Additive manufacturing is expanding beyond mechanical prosthetics into microelectronic implants. This work presents a diamond‐titanium hybrid that enables wireless power transfer, localized heating, and flow sensing. The use of additive manufacturing combined with the biocompatibility of the diamond‐titanium hybrid material paves the way toward new ...
Joshua Zarins   +9 more
wiley   +1 more source

Exploiting the Functionality of Cerium Oxide‐Modified Carbon Nanohorns Catalysts Toward Enhanced CO2 Reduction Performance

open access: yesAdvanced Functional Materials, EarlyView.
A cerium oxide‐carbon nanohybrid catalyst is synthesized via two distinct routes and is integrated into H‐type cells and gas diffusion layers (GDLs) to enhance electrochemical performance. Structural variations significantly affect performance, with the solvothermal sample exhibiting higher current densities.
Alessia Pollice   +9 more
wiley   +1 more source

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