Results 51 to 60 of about 150,531 (265)

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Artery‐on‐Chip Demonstrates Mechanical and Functional Features of Healthy and Diseased Living Smooth Muscle Tissue

Advanced Functional Materials, EarlyView.
This article details the development of an artery‐on‐chip platform for in vitro arterial disease modeling and therapeutic discovery. It describes the fabrication of a fibrin biomaterial scaffold seeded with iPSC‐derived smooth muscle and endothelial cells, mimicking native artery properties. Two genetic disease models showcase the platform's ability to
Danielle Yarbrough, Roy Chen, Katerina Katsouleas, Jaron Shoemaker, Travis Brady, Tianfang Yu, Jennifer Arthur Ataam, Connor Amelung, Lakshmi Santhanam, Ioannis Karakikes, Sharon Gerecht   +10 more
wiley   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Programmable biomaterials for bone regeneration

Materials Today Bio
Programmable biomaterials are distinguished by their ability to adjust properties and functions on demand, in a periodic, reversible, or sequential manner.
Peiran Song, Dongyang Zhou, Fuxiao Wang, Guangfeng Li, Long Bai, Jiacan Su   +5 more
doaj   +1 more source

Efficacy of intraoperatively prepared cell-based constructs for bone regeneration

Stem Cell Research & Therapy, 2018
Background Conventional cell-based bone regeneration suffers from the major disadvantage of limited cell supply, time-consuming in vitro expansion cultures, and limited patient-friendliness related to cell isolation and multiple visits to the clinic ...
Yang Zhang, Eline C Grosfeld, Winston A Camargo, Hongbo Tang, Angela M P Magri, Jeroen J J P van den Beucken   +5 more
doaj   +1 more source

Functional Nanofibrous Biomaterials of Tailored Structures for Drug Delivery—A Critical Review

Pharmaceutics, 2020
Nanofibrous biomaterials have huge potential for drug delivery, due to their structural features and functions that are similar to the native extracellular matrix (ECM).
Zhen Li, Shunqi Mei, Yajie Dong, Fenghua She, Yongzhen Li, Puwang Li, Lingxue Kong   +6 more
doaj   +1 more source

Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay. [PDF]

PLoS ONE, 2012
Bioactive bone substitute materials are a valuable alternative to autologous bone transplantations in the repair of skeletal defects. However, clinical studies have reported varying success rates for many commonly used biomaterials.
Johannes Keller, Silja Brink, Björn Busse, Arndt F Schilling, Thorsten Schinke, Michael Amling, Tobias Lange   +6 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Sustainable Materials and Technologies for Biomedical Applications

Advances in Materials Science and Engineering, 2023
Over the past few years, 3D-printed biomaterials have gained widespread usage in the manufacturing of orthopaedic implants. 3D-printed implants have low weight, minimal material waste, ease of creation, the capacity to create complex topological implants
Pralhad Pesode, Shivprakash Barve, Sagar V. Wankhede, Akbar Ahmad   +3 more
doaj   +1 more source

Demonstrating Vibrational Current Generation With a Self‐Assembled Bioelectret

Advanced Functional Materials, EarlyView.
Vacuum‐deposited films of the plant‐derived molecule, Baicalein, form a self‐assembled bioelectret exhibiting spontaneous orientation polarization and a giant surface potential. The films induce alternating current during the vibration of a movable electrode without charging treatments. Hydrocarbon protection enhances the air stability of the Baicalein
Kouki Akaike, Yukihiro Shimoi, Qingshuo Wei, Yutaro Ono, Satomi Hosono, Yoichi Yamada, Haruhisa Akiyama, Shunsuke Tanaka   +7 more
wiley   +1 more source