Results 41 to 50 of about 183,893 (316)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Deep multimodal biomechanical analysis for lower back pain rehabilitation to improve patients stability

Frontiers in Bioengineering and Biotechnology
IntroductionAdvancements in artificial intelligence are transforming rehabilitation by enabling scalable, patient-centric solutions within modern healthcare systems.
Muhammad Abrar Ashraf, Muhammad Abrar Ashraf, Yanfeng Wu, Shaheryar Najam, Mohammed Alshehri, Yahya AlQahtani, Hanan Aljuaid, Ahmad Jalal, Ahmad Jalal, Hui Liu, Hui Liu, Hui Liu   +11 more
doaj   +1 more source

A Biomechanical Analysis of the Free Throw Shooting Technique in Wheelchair Basketball: A Pilot Study

Journal of Anthropology of Sport and Physical Education, 2022
The aim of this pilot study is to determine the kinematic elements of the free throw shooting technique among wheelchair basketball players from various classes.
Nikola Prvulovic, Miljan Hadzovic, Ana Lilic   +2 more
doaj   +1 more source

The effect of military load carriage on ground reaction forces [PDF]

, 2007
Load carriage is an inevitable part of military life both during training and operations. Loads carried are frequently as high as 60% bodyweight, and this increases injury risk. In the military, load is carried in a backpack (also referred to as a Bergen)
Haslam, Roger, Haslam, RA, Hooper, RH, Birrell, Stewart A., Birrell, SA, Hooper, Robin H.   +5 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Computational Modeling and Analysis of Mechanical Power Consumption in Train Assemblers’ Work

Proceedings of the International Conference on Applied Innovations in IT
This study presents computational and biomechanical models to analyze mechanical power consumption in train assemblers' work at railway stations. The research integrates physical and mathematical modeling to quantify energy expenditure based on movement ...
Miraziz Talipov
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

A three-dimensional finite element model of maximal grip loading in the human wrist

, 2009
The aim of this work was to create an anatomically accurate three-dimensional finite element model of the wrist, applying subject-specific loading and quantifying the internal load transfer through the joint during maximal grip.
Condon, B., D H Nash, M K Gislason, Hems, T., Kanellopoulos, A., B Condon, Stansfield, Ben W., Nicol, A., A Nicol, Bransby-Zachary, M., M Bransby-Zachary, Nicol, A.C., Gislason, M. K., Gislason, Magnus K., T Hems, B Stansfield, Nash, D.H., Stansfield, B., Nash, D. H., A Kanellopoulos   +19 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Sex Differences Exist in the Relationship Between Vertical Jump Performance Biomechanical Parameters and Hamstring/Quadriceps Ratio in Adolescent U18 Track and Field Athletes

Sports
Isokinetic metrics are suggested to be related to vertical jump performance, but little is known about the possible sex differences in this relationship in adolescent track and field athletes.
Vassilios Panoutsakopoulos, Mariana C. Kotzamanidou, Vasiliki Manou   +2 more
doaj   +1 more source