Results 71 to 80 of about 2,917,391 (330)

The utility of the nitric oxide electrochemical sensor in biomedical research [PDF]

, 2003
In recent years World Precision Instruments Inc. (WPI) produced for commercial use a selective and sensitive electrochemical sensor for the detection of the important biological free radical nitric oxide (NO).
Clark, JB, Hurst, RD
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Biomedical mass spectrometry [PDF]

Analytical and Bioanalytical Chemistry, 2012
The 37th Annual Meeting of the Japanese Society for Biomedical Mass Spectrometry (JSBMS) was held on October 25th and 26th, 2012, in Aichi Industry and Labor Center (WINC AICHI), Nagoya, Japan. We aimed for extensive discussions and interdisciplinary cooperation for the researchers in the wide range of areas involved in mass spectrometry; the topics in
Toyofumi, Nakanishi, Mitsutoshi, Setou, Tomiko, Kuhara   +2 more
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Comprehensive Review of Hybrid Feature Selection Methods for Microarray-Based Cancer Detection

IEEE Access
Microarray data-based cancer detection advances early diagnosis and personalized medicine by utilizing gene expression data to develop comprehensive cancer profiles, measuring thousands of genes simultaneously.
Azka Khoirunnisa, Didit Adytia, Mustafa Mat Deris, Adiwijaya   +3 more
doaj   +1 more source

Review of Electroanalytical-Based Approaches for the Determination of Benzodiazepines

Biosensors, 2019
The benzodiazepine class of drugs are characterised by a readily electrochemically reducible azomethine group. A number are also substituted by other electrochemically active nitro, N-oxide, and carbonyl groups, making them readily accessible to ...
Kevin C. Honeychurch
doaj   +1 more source

New desiderata for biomedical terminologies [PDF]

, 2008
It is only by fixing on agreed meanings of terms in biomedical terminologies that we will be in a position to achieve that accumulation and integration of knowledge that is indispensable to progress at the frontiers of biomedicine.
Smith, Barry
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A Reduction Method of Phantom Shell Effects for APD Extraction Using Negative Permittivity Material

IEEE Access
This paper proposes a method to reduce phantom shell effects that occur during the absorbed power density (APD) derivation using a negative permittivity material (NPM).
Changmin Lee, Jaewon Rhee, Hyukchoon Kwon, Yongho Park, Seungyoung Ahn   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source