Results 51 to 60 of about 1,071,500 (344)

Biomechanical motion analysis in the clinical environment : the dawn of a new era ? [PDF]

open access: yes, 2012
Philip Rowe looks at biomechanical motion analysis and the work the department of Biomedical engineering at the University of Strathclyde, Glasgow, UK (formerly the Bioengineering Unit), has played a key role in these developments over the last 50 ...
Rowe, Philip
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Biomedical Engineering And Its Potential For Employment in Indonesia

open access: yesInternational Journal of Technology, 2014
Indonesia, as cited by the World Health Organization (WHO), is still listed as one of the countries who spend less of its GDP on health services, despite the urgent need to overcome the high rate of medical cases in several diseases.
Maria Elfani, Narendra Kurnia Putra
doaj   +1 more source

Problem-Oriented Modelling for Biomedical Engineering Systems

open access: yesApplied Sciences, 2022
Technical system (TS) models are widely used for setting and solving problems for the improvement of biomedical engineering systems beyond simple parameter optimisation. They mostly focus on system elements, the change or replacement of which can provide
Ivan Kernytskyy   +11 more
doaj   +1 more source

Development and Transfer of Innovative Problem Solving Strategies and Related Confidence in Biomedical Engineering [PDF]

open access: yes, 2019
Twenty-nine biomedical engineering (BME) undergraduates participated in a challenge-based instruction biotransport course, offered by the UT Austin BME Department in an accelerated format, at the University of Cambridge.
Clegg, John R., Diller, Kenneth R.
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A 2009 survey of the Australasian clinical medical physics and biomedical engineering workforce [PDF]

open access: yes, 2010
A survey of the Australasian clinical medical physics and biomedical engineering workforce was carried out in 2009 following on from a similar survey in 2006.
Round, W. Howell
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

BME STATS Fall 2010 [PDF]

open access: yes, 2010
https://digitalcommons.fiu.edu/bme_stats/1000/thumbnail ...
Department of Biomedical Engineering, Florida International University
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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