Results 71 to 80 of about 2,826,290 (328)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Analysis of uncertainty and variability in finite element computational models for biomedical engineering:characterization and propagation

open access: yesFrontiers in Bioengineering and Biotechnology, 2016
Computational modeling has become a powerful tool in biomedical engineering thanks to its potential to simulate coupled systems. However, real parameters are usually not accurately known and variability is inherent in living organisms. To cope with this,
Nerea Mangado   +5 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Multidisciplinary Learning Extends Communication Skill, and Helps Cross Cultural Understandings: Biomedical Engineering [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2017
The effects of multidisciplinary learning on extension of communication skill and on cross-cultural understandings have been discussed. "Biomedical engineering" is exemplified for the multidisciplinary field, which includes biology, medicine, engineering,
Shigehiro Hashimoto
doaj  

“Plasmonic Nanomaterials”: An emerging avenue in biomedical and biomedical engineering opportunities

open access: yesJournal of Advanced Research, 2022
Background: Plasmonic nanomaterials as noble metal-based materials have unique optical characteristic upon exposure to incident light with an appropriate wavelength.
Yasaman-Sadat Borghei   +2 more
doaj  

Using Virtual Reality in Biomedical Engineering Education.

open access: yesJournal of Biomechanical Engineering, 2020
This study explored virtual reality (VR) as an educational tool to offer immersive and experiential learning environments to biomedical engineering (BME) students.
Anita Singh   +3 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Empathy and ethical becoming in biomedical engineering education: a mixed methods study of an animal tissue harvesting laboratory

open access: yesAustralasian Journal of Engineering Education, 2020
Biomedical engineering presents a unique context for ethics education due to the human-centric nature of biomedical engineering coupled with the pervasiveness of animal-based practices.
J. Hess   +4 more
semanticscholar   +1 more source

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