Results 101 to 110 of about 373,598 (290)

Nanostructures: Enhancing Potential Applications in Biomedicals

open access: yesJournal of Biomaterials and Nanobiotechnology, 2013
Nanotechnology is defined as the study and application of 1 - 100 nm sized structures. Nanomaterials have opened avenues for the industries and scientific endeavors. These recognized for unique size, dependant physical and chemical properties (optical, magnetic, catalytic, thermodynamic, electrochemical) [1].
openaire   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

A Survey of Machine Learning Techniques Leveraging Brightness Indicators for Image Analysis in Biomedical Applications

open access: yesIEEE Access
This paper presents a comprehensive survey of machine-learning techniques that leverage brightness indicators for image analysis within biomedical applications.
Hajer Ghodhbani   +3 more
doaj   +1 more source

Developing Human Functioning and Rehabilitation Research from the comprehensive perspective. [PDF]

open access: yes, 2007
With the International Classification of Functioning, Disability and Health (ICF) the World Health Organization (WHO) has prepared the ground for a comprehensive understanding of Human Functioning and Rehabilitation Research, integrating the biomedical ...
Grimby, Gunnar   +3 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Recent advances in thermomechanical properties of PLA-based biopolymer composites for biomedical applications

open access: yesNext Materials
Biopolymer composites have become promising materials in recent years owing to their biomedical properties, including tunable mechanical properties, biocompatibility, and biodegradability. The thermomechanical characteristics of biopolymer composites are
Md. Osman Ali   +9 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Effective type label-based synergistic representation learning for biomedical event trigger detection

open access: yesBMC Bioinformatics
Background Detecting event triggers in biomedical texts, which contain domain knowledge and context-dependent terms, is more challenging than in general-domain texts. Most state-of-the-art models rely mainly on external resources such as linguistic tools
Anran Hao   +3 more
doaj   +1 more source

Nano-carriers for Targeted Delivery and Biomedical Imaging Enhancement

open access: yesTherapeutic Delivery, 2018
Theranostic approaches using nanotechnology have been a hot research area for the past decade. All nano drug delivery techniques and architectures have some limitations, as do diagnostic nano-approaches. Thus, combining nano drug delivery strategies with diagnostic techniques using nanoparticles for improving imaging modalities has been the key to fill
Parekh Gaurav   +4 more
openaire   +3 more sources

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