Results 81 to 90 of about 162,788 (297)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Linear Invariant Systems Theory for Signal Enhancement

, 2011
This paper discusses a linear time invariant (LTI) systems approach to signal enhancement via projective subspace techniques. It provides closed form expressions for the frequency response of data adaptive finite impulse response eigenfilters.
Lang, Elmar W., Georgieva, P., Teixeira, A. J. S., Miguel, G., Tomé, A.M., Teixeira, Ana Rita   +5 more
core  

Latent Fingerprint Enhancement Using Tripolyphosphate-Chitosan Microparticles [PDF]

, 2013
Chitosan has been widely used in the preparation of microparticles for drug delivery; however, it has not been considered in forensic applications. Tripolyphosphate- (TPP-) chitosan microparticles were formed using ionotropic gelation in the presence of ...
Il Dueik, Issa M. A., Morris, Gordon A.
core   +1 more source

A 1.2v ΔΣ ADC Modulator Using 4-bit SAR Quantizer for Biomedical Applications by using 65nm CMOS Technology [PDF]

MATEC Web of Conferences
This research focuses on enhancing Sigma-Delta ADC modulators for biomedical applications by leveraging the working principle of Successive Approximation ADC circuits.
Lakshmi Bhavani G., Muzafar Patan, Usha Rani T., Siddarath Reddy K., Prathusha K., Pavani Pasupuleti, Kumar Manish   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Automated analysis of atrial late gadolinium enhancement imaging that correlates with endocardial voltage and clinical outcomes: A 2-center study [PDF]

, 2013
This work was supported by the British Heart Foundation PG/10/37/28347, RG/10/11/28457, NIHR Biomedical Research Centre funding, and the ElectroCardioMaths Programme of the Imperial BHF Centre of Research ...
Peters, NS, Petersen, SE, Kojodjojo, P., Quest, R, Hunter, R., Petersen, S.E., Karim, R, Quest, R., Lim, PB, Ariff, B., Francis, D.P., Malcolme-Lawes, L.C., Kanagaratnam, P., Juli, C., Schilling, R, Karim, R., Boubertakh, R., Schilling, R., Bai, W, Lim, P.B., Francis, DP, Jamil-Copley, S., Peters, N.S., Rueckert, D, Kanagaratnam, P, Bai, W., Malcolme-Lawes, LC, Davies, D.W., Davies, DW, Boubertakh, R, Jones, D., Juli, C, Kojodjojo, P, Hunter, R, Rueckert, D., Jamil-Copley, S, Ariff, B, Jones, D   +37 more
core   +1 more source

Moral Perfection and the Demand for Human Enhancement

Ethics in Progress, 2015
In this article I discuss one of the most significant areas of bioethical interest, which is the problem of moral enhancement. Since I claim that the crucial issue in the current debate on human bioenhancement is the problem of agency, I bring out and ...
Adriana Warmbier
doaj   +3 more sources

Experimental test of the entanglement enhancement in two-photon fluorescence

Quantum Frontiers
Entangled photons with time-energy correlations are predicted to have improved sensitivity compared with classical light in two-photon fluorescence, which is promising for lowering the phototoxicity in biomedical imaging.
Gewei Qian, Xiao Liu, Chenran Xu, Xingqi Xu, Da-Wei Wang   +4 more
doaj   +1 more source