Results 61 to 70 of about 373,598 (290)

Tensor Methods in Biomedical Image Analysis

open access: yesJournal of Medical Signals and Sensors
In the past decade, tensors have become increasingly attractive in different aspects of signal and image processing areas. The main reason is the inefficiency of matrices in representing and analyzing multimodal and multidimensional datasets.
Farnaz Sedighin
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Porous carbon nanowire array for surface-enhanced Raman spectroscopy

open access: yesNature Communications, 2020
SERS can be unreliable for biomedical use. The authors demonstrate a metal-free nanostructure composed of porous carbon nanowires in an array as a SERS substrate.
Nan Chen   +8 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Beyond humanity?: the ethics of biomedical enhancement

open access: yesRevista de Direito Sanitário, 2011
Resenha ...
SPIEKERMANN, Kai
doaj  

Flexible and Wearable Antenna for Biomedical Application: Progress and Opportunity

open access: yesIEEE Access
In recent years, wearable antenna demand in biomedical applications has increased drastically. Several effective techniques and efficient structures of antenna were proposed to overcome the challenges with respect to the vicinity of the human body.
A. L. Sharon Giftsy   +2 more
doaj   +1 more source

Organism–Materials Integration: A Promising Strategy for Biomedical Applications

open access: yesAdvanced NanoBiomed Research, 2021
In nature, organisms play an essential role in harnessing elements to produce materials. Being precisely integrated with the biological structures, the materials confer organisms with various unique functions such as protection, recognition guiding ...
Yihao Cui   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Visual storytelling enhances knowledge dissemination in biomedical science

open access: yesJournal of Biomedical Informatics, 2020
Research findings in biomedical science are often summarized in statistical plots and sophisticated data presentations. Such visualizations are challenging for people who lack the appropriate scientific background or even experts who work in other areas.
Taxiarchis Botsis   +3 more
openaire   +2 more sources

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