Results 71 to 80 of about 162,788 (297)

Interactive Evolutionary Algorithms for Image Enhancement and Creation [PDF]

open access: yes, 2014
Image enhancement and creation, particularly for aesthetic purposes, are tasks for which the use of interactive evolutionary algorithms would seem to be well suited.
Mist, Joseph James
core  

Beyond humanity?: the ethics of biomedical enhancement

open access: yesRevista de Direito Sanitário, 2011
Resenha ...
SPIEKERMANN, Kai
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Porous carbon nanowire array for surface-enhanced Raman spectroscopy

open access: yesNature Communications, 2020
SERS can be unreliable for biomedical use. The authors demonstrate a metal-free nanostructure composed of porous carbon nanowires in an array as a SERS substrate.
Nan Chen   +8 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Flexible and Wearable Antenna for Biomedical Application: Progress and Opportunity

open access: yesIEEE Access
In recent years, wearable antenna demand in biomedical applications has increased drastically. Several effective techniques and efficient structures of antenna were proposed to overcome the challenges with respect to the vicinity of the human body.
A. L. Sharon Giftsy   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Organism–Materials Integration: A Promising Strategy for Biomedical Applications

open access: yesAdvanced NanoBiomed Research, 2021
In nature, organisms play an essential role in harnessing elements to produce materials. Being precisely integrated with the biological structures, the materials confer organisms with various unique functions such as protection, recognition guiding ...
Yihao Cui   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Thermal Image Enhancement using Bi-dimensional Empirical Mode Decomposition in Combination with Relevance Vector Machine for Rotating Machinery Fault Diagnosis [PDF]

open access: yes, 2009
In this study, a novel fault diagnosis system for rotating machinery using thermal imaging is proposed. This system consists of bi-dimensional empirical mode decomposition (BEMD) for image enhancement, a generalized discriminant analysis (GDA) for ...
Yang, Bo-Suk   +7 more
core   +1 more source

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