Results 31 to 40 of about 132,548 (311)

Brain–computer interface for simultaneous dual‐region spatial coding in hippocampal and somatosensory cortex of freely behaving rats

Electronics Letters
Decoding of spatial information from place cells is currently limited to individual brain regions, severely constraining the understanding of the brain's spatial navigation mechanisms.
Ming Li, Wei Xu, Zhaojie Xu, Fan Mo, Gucheng Yang, Shiya Lv, Hanwen Cao, Juntao Liu, Xinxia Cai   +8 more
doaj   +1 more source

Applications of nanogenerators for biomedical engineering and healthcare systems

InfoMat, 2022
The dream of human beings for long living has stimulated the rapid development of biomedical and healthcare equipment. However, conventional biomedical and healthcare devices have shortcomings such as short service life, large equipment size, and high ...
Wanli Wang, Jinbo Pang, Jie Su, Fujiang Li, Qiang Li, Xiaoxiong Wang, Jingang Wang, Bergoi Ibarlucea, Xiaoyan Liu, Yufen Li, Weijia Zhou, Kai Wang, Qingfang Han, Lei Liu, Ruohan Zang, Mark H. Rümmeli, Yang Li, Hong Liu, Han Hu, Gianaurelio Cuniberti   +19 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Internet of Things-Based Electromagnetic Compatibility Monitoring (IEMCM) Architecture for Biomedical Devices

Applied Sciences
Electromagnetic compatibility is the capability of electrical and electronic equipment to function properly around devices radiating electromagnetic energy, without mutual disturbance.
Chiedza Hwata, Gerard Rushingabigwi, Omar Gatera, Didacienne Mukalinyigira, Celestin Twizere, Bolaji N. Thomas, Diego H. Peluffo-Ord’onez   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Medical Device Safety Management Using Cybersecurity Risk Analysis

IEEE Access, 2020
Hospital biomedical engineering teams are responsible for establishing and regulating medical equipment management programs (MEMPs); these programs ensure the safety and reliability of medical devices.
Dong-Won Kim, Jin-Young Choi, Keun-Hee Han   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Augmented reality-based feedback for technician-in-the-loop C-arm repositioning

Healthcare Technology Letters, 2018
Interventional C-arm imaging is crucial to percutaneous orthopedic procedures as it enables the surgeon to monitor the progress of surgery on the anatomy level.
Mathias Unberath, Javad Fotouhi, Javad Fotouhi, Jonas Hajek, Andreas Maier, Greg Osgood, Russell Taylor, Mehran Armand, Nassir Navab   +8 more
doaj   +1 more source