Results 61 to 70 of about 677,625 (300)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Advanced Electronic MaterialsLoneliness is a critical issue among older people and poses a significant risk factor for various physical and mental health conditions. While recent wearable technologies can monitor behavioral and physiological changes associated with loneliness ...
Yi Zhou +12 more
doaj +1 more source
Bioengineering, 2023 Adaptive deep brain stimulation (aDBS) is a promising concept in the field of DBS that consists of delivering electrical stimulation in response to specific events.
José Ángel Ochoa +3 more
doaj +1 more source
Electromagnetic coupling simulagions for a magnetic induction sensor for sleep monitoring [PDF]
, 2014 Magnetic induction (MI) method has been extensively used in non-destructive testing of materials. In biomedical applications, it attracted lots of attention for the contact-less advantages it provides.
Mahdavi, Hadiseh +1 more
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey [PDF]
Lateral flow (immuno)assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring in resource-poor or non-laboratory environments.
Amerongen, A., van +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Advances in Optical Biomedical Sensing Technology [PDF]
, 2016 A study of the global healthcare trends shows that more people need health care across different ages and nations of the World. Therefore, there is a rapid growth and expansion of Healthcare Industry globally.
Agboje, O. E., Takpor, Temitope
core
Goal-directed therapy in intraoperative fluid and hemodynamic management. [PDF]
, 2013 Intraoperative fluid management is pivotal to the outcome and success of surgery, especially in high-risk procedures. Empirical formula and invasive static monitoring have been traditionally used to guide intraoperative fluid management and assess volume
Gutierrez, Maria Cristina +2 more
core +1 more source