Results 101 to 110 of about 2,344,465 (331)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
ДИСТАНЦИОННЫЙ ФОРМАТ В ПРЕПОДАВАНИИ НОРМАЛЬНОЙ ФИЗИОЛОГИИ
В статье представлен анализ опыта организации преподавания нормальной физиологии в дистанционном (онлайн) формате в период пандемии новой коронавирусной инфекции COVID-19 в 2020-2021 и 2021-2022 учебных годах.
Валерий Олегович Еркудов +11 more
doaj
Priorities in biomedical research. Indices of burden. [PDF]
Danae Black, Jason D. Pole
openalex +1 more source
Biomedical research publications: 1980 - 1982 [PDF]
Publications concerning the major physiological and psychological problems encountered by man when he undertakes space flight are listed. Nine research areas are included: cardiovascular deconditioning, motion sickness, bone alterations, muscle atrophy ...
Limbach, L., Pleasant, L. G.
core +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Clinical investigations for SUS, the Brazilian public health system
CONTEXT AND OBJECTIVE: Scientific and technological development is crucial for advancing the Brazilian health system and for promoting quality of life. The way in which the Brazilian Ministry of Health has supported clinical research to provide autonomy,
Ana Patrícia de Paula +10 more
doaj +1 more source
Почечно -клеточная карцинома составляет 97% от всех опухолей почки у взрослых людей. Ведущую роль в лечении почечно -клеточной карциномы занимает хирургическая резекция первичной опухоли, однако не для всех пациентов применимо данное лечение.
Армен Алексанович Овсепян +5 more
doaj
Naval Biomedical Research Laboratory, Programmed Environment, Aerosol Facility [PDF]
L. J. Goldberg
openalex +1 more source
The realm of biomaterials, under which biomedical materials can be categorised, has a broad definition base and recognises materials that are synthesized or naturally sourced.
Mucalo, Michael R., Worth, Andrew J.
core
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source

