Results 101 to 110 of about 1,215,832 (310)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Wearable Sensor-Based Exercise Biofeedback for Orthopaedic Rehabilitation: A Mixed Methods User Evaluation of a Prototype System

Sensors, 2019
The majority of wearable sensor-based biofeedback systems used in exercise rehabilitation lack end-user evaluation as part of the development process.
Rob Argent, Patrick Slevin, Antonio Bevilacqua, Maurice Neligan, Ailish Daly, Brian Caulfield   +5 more
doaj   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Saúde e inovação: uma abordagem sistêmica das indústrias da saúde

Cadernos de Saúde Pública
Partindo do reconhecimento da importância da geração e da difusão de inovações para o desenvolvimento sócio-econômico nos países capitalistas e do caráter sistêmico, institucional e histórico desse processo, o trabalho procura evidenciar a necessidade de
Carlos Augusto Grabois Gadelha, Cristiane Quental, Beatriz de Castro Fialho   +2 more
doaj  

A Bibliometric Study to Assess Bioprinting Evolution

Applied Sciences, 2017
Bioprinting as a tissue engineering tool is one of the most promising technologies for overcoming organ shortage. However, the spread of populist articles among on this technology could potentially lead public opinion to idealize its readiness.
Adrien Naveau, Rawen Smirani, Sylvain Catros, Hugo de Oliveira, Jean-Christophe Fricain, Raphael Devillard   +5 more
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Desenvolvimento de um dispositivo eletrônico para organizar medicamentos e promover a adesão medicamentosa

Revista Panamericana de Salud Pública
RESUMO O presente artigo descreve o desenvolvimento de um protótipo eletrônico para organizar medicamentos, denominado Sistema Eletrônico de Uso Personalizado e Controlado de Medicamentos (SUPERMED).
Liliana Batista Vieira, Celso de Ávila Ramos, Matheus de Barros Castello, Lorenzo Couto do Nascimento   +3 more
doaj  

Evaluating Deep Learning Architectures for Breast Tumor Classification and Ultrasound Image Detection Using Transfer Learning

Big Data and Cognitive Computing
The intersection of medical image classification and deep learning has garnered increasing research interest, particularly in the context of breast tumor detection using ultrasound images. Prior studies have predominantly focused on image classification,
Christopher Kormpos, Fotios Zantalis, Stylianos Katsoulis, Grigorios Koulouras   +3 more
doaj   +1 more source

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh, Yoon Hee Shin, Soo Hyun Ahn, Su Yee Mon, Soo Jean Shin, Woo‐Jin Lee, Yoonhyuk Jang, Myoung‐Jin Jang, Soon‐Tae Lee   +8 more
wiley   +1 more source

Channel swapping of EEG signals for deep learning‐based seizure detection

Electronics Letters
The purpose of epilepsy detection is to determine whether epilepsy has occurred by analysing the patient's electroencephalogram (EEG) signals. Compared to traditional methods, epilepsy detection methods based on deep learning have achieved significant ...
Yayan Pan, Fangying Dong, Wei Yao, Xiaoqin Meng, Yongan Xu   +4 more
doaj   +1 more source