Results 91 to 100 of about 1,046,306 (342)

Reliability of Quality Assessments in Research Synthesis: Securing the Highest Quality Bioinformation for HIT. [PDF]

, 2012
Current trends in bio-medicine include research synthesis and dissemination of bioinformation by means of health (bio) information technology (H[b] IT). Research must secure the validity and reliability of assessment tools to quantify research quality in
Arora, Rashi, Barkhordarian, André, Chiappelli, Francesco, Giroux, Amy, Kung, Jason, Phi, Linda, Phil, C, Ramchandani, Manisha, Uyeda, Molly   +8 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Evaluación de tecnologías diagnósticas: conceptos básicos en un estudio con muestreo transversal Assessing a diagnostic test: basic concepts in a study with naturalistic sampling

Revista Colombiana de Obstetricia y Ginecología, 2007
Los estudios de evaluación de pruebas diagnósticas son un diseño científico que nos ayuda a determinar la validez y la reproducibilidad de los procedimientos que pueden ser usados en la práctica clínica por médicos y otros profesionales de salud. Este es
María Isabel Castro-Jiménez, Daladier Cabrera-Rodríguez, Miguel Ángel Castro-Jiménez   +2 more
doaj  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

What's unusual in online disease outbreak news? [PDF]

, 2010
Background: Accurate and timely detection of public health events of international concern is necessary to help support risk assessment and response and save lives.
Collier, Nigel
core   +4 more sources

A Global View of Standards for Open Image Data Formats and Repositories [PDF]

arXiv, 2020
Biological and biomedical imaging datasets record the constitution, architecture and dynamics of living organisms across several orders of magnitude of space and time. Imaging technologies are now used throughout the life and biomedical sciences to achieve discovery and understanding of biological mechanisms in the basic sciences as well as assessment,
arxiv  

The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]

, 2019
Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir, Emamian, Sattar S., Fotovvati, Behzad, Gisario, Annamaria, Mehrpouya, Mehrsha, Vosooghnia, Alireza   +5 more
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Dissemination of evidence-based standards of care. [PDF]

, 2011
Standards of care pertain to crafting and implementing patient-centered treatment interventions. Standards of care must take into consideration the patient's gender, ethnicity, medical and dental history, insurance coverage (or socioeconomic level, if a ...
Barkhordarian, Andre, Chiappelli, Francesco, Hacker, Brett   +2 more
core   +3 more sources