Results 161 to 170 of about 43,712,030 (248)

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, Volume 13, Issue 62, 9 November 2026.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, Volume 13, Issue 63, 12 November 2026.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Can LLMs automate data extraction in agronomic meta‐analyses? A feasibility study on cover crops and soybean yield

Agronomy Journal, Volume 118, Issue 6, November/December 2026.
Abstract Large language models (LLMs) can streamline article screening and data extraction to accelerate meta‐analysis synthesis; however, their use remains limited in agrisciences. In this study, we evaluated the potential of LLMs to accurately extract data from articles of a published meta‐analysis.
Tatiane Severo Silva, Fabiano Colet, Jason Chor Ming Lo, Spyridon Mourtzinis, Damon L. Smith, Matheus de Freitas Souza, Shawn Conley   +6 more
wiley   +1 more source

Framing anatomical variation in anatomy textbooks: Language use and its implications

Anatomical Sciences Education, Volume 19, Issue 11, Page 2055-2063, November 2026.
Text mining of anatomy textbooks shows “abnormal” is the most frequently used descriptor for anatomical variation, reinforcing a binary framing. We advocate for explicit teaching of variation as a spectrum, with consistent, neutral terminology and contextualization (prevalence and functional relevance) to support a more nuanced understanding of ...
An‐Di Yim, Matthew Schell, Alexandra Zachwieja   +2 more
wiley   +1 more source

Ritualized reflection in human dissection: Liminality, ethical negotiation, and professional identity formation among South Korean medical students

Anatomical Sciences Education, Volume 19, Issue 11, Page 1998-2007, November 2026.
Abstract Human dissection is a foundational component of medical education, yet it places students in profound ethical tension between scientific objectification and respect for human dignity. While prior studies have documented students' emotional responses, the structural transformation of their moral narratives over time, particularly within non ...
Jun‐Ki Lee, Hyoungtae Kim, Hyo Hyun Yoo   +2 more
wiley   +1 more source

Contextual Semantic Pattern Recognition for Mental Health Monitoring Using ClinicalBERT Transformers

Brain and Behavior, Volume 16, Issue 11, November 2026.
ABSTRACT Purpose This study aimed to develop an interpretable ClinicalBERT‐based framework for mental health monitoring using structured clinical data. Method Because the Mental Health Diagnosis and Treatment Monitoring dataset contains structured patient attributes rather than free‐text clinical narratives, a structured‐to‐text transformation module ...
Junjun Sun
wiley   +1 more source

Evidence Mapping, Certainty Appraisal, and Acupoint Prescription Pattern Mining of Acupuncture for Poststroke Dysphagia: An Overview of Systematic Reviews

Brain and Behavior, Volume 16, Issue 11, November 2026.
This overview mapped evidence from 45 systematic reviews/meta‐analyses of acupuncture for post‐stroke dysphagia and appraised quality, certainty, overlap, and prescription patterns. Findings suggest potential adjunctive benefits but limited confidence, highlighting the need for rigorous trials and standardized swallowing‐related outcomes.
Guohao Lan, Minmin Wu, Jiongliang Zhang, Yuxuan Li, Yuting Wang, Yumeng Su, Zhiliang Dong, Xiangyu Wei, Luwen Zhu   +8 more
wiley   +1 more source

Multimodal Deep Learning Approach Using Laser Doppler Flowmetry, Fluorescence Spectroscopy, and Clinical Data for Multi‐Class Mental Health and Severity Classification

Engineering Reports, Volume 8, Issue 11, November 2026.
X‐DyFGate introduces adaptive cross‐modal fusion of physiological and clinical information for personalized mental health assessment. The framework combines cross‐attention, dynamic feature gating, and interpretable multimodal learning to achieve highly accurate and clinically meaningful predictions.
Kavitha Suresh Jayasree, Nagarajan Bharanidharan   +1 more
wiley   +1 more source

A FAIR gold-standard benchmark for geographic entity recognition in cancer genomics literature for biomedical NLP. [PDF]

Bioinform Adv
Kann MG, O'Connor K, Tembei P, Rosner S, Gonzalez Hernandez G.   +4 more
europepmc   +1 more source

Understanding Drivers of Loss to Follow‐Up in HIV Care in Oromia Regional State, Ethiopia: A Qualitative Grounded Theory

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background Despite significant advancements in antiretroviral therapy (ART), loss to follow‐up (LTFU) remains a critical challenge in HIV care, particularly in low‐resource settings like Ethiopia. LTFU contributes to increased morbidity and mortality rates, heightened transmission risks, and treatment failure.
Fikru Tafese, Matebu Gezahegn, Zeriun Kura, Eshetu Alemayehu, Yadeta Ayana, Chala Bafikadu, Gusha Belako, Tesfaye Zerfu, Birhanu Kenate Sori, Yadeta Dassie, Firaol Bekele, Negash Sime, Tizta Tilahun Degfie, Daniel Yilma, Yohannes Ejigu, Yohannes Kebede, Mirkuzie Woldie   +16 more
wiley   +1 more source