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Engineering Micro–Nanomaterials for Biomedical Translation [PDF]

open access: yesAdvanced NanoBiomed Research, 2021
Engineered nano–bio interfaces–driven by vertical micro/nanoneedles, nanoparticles, organ‐on‐chip devices, and a diversity of nanosubstrates for mass spectroscopy imaging–are spurring scientific and technological progress, from fundamental to ...
Yaping Chen   +8 more
doaj   +2 more sources

Methods for identifying biomedical translation: a systematic review. [PDF]

open access: yesAm J Transl Res, 2022
Translational medicine is an important area of biomedicine, and has significantly facilitated the development of biomedical research. Despite its relevance, there is no consensus on how to evaluate its progress and impact. A systematic review was carried out to identify all the methods to evaluate translational research.
Padilla-Cabello J   +5 more
europepmc   +3 more sources

Nanoparticles for Biomedical Imaging: Fundamentals of Clinical Translation

open access: yesMolecular Imaging, 2010
Because of their large size compared to small molecules and their multifunctionality, nanoparticles (NPs) hold promise as biomedical imaging, diagnostic, and theragnostic agents.
Hak Soo Choi, John V. Frangioni
doaj   +3 more sources

A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies

open access: yesJournal of Biomedical Science, 2022
The novel coronavirus disease (COVID-19) pandemic remains a global public health crisis, presenting a broad range of challenges. To help address some of the main problems, the scientific community has designed vaccines, diagnostic tools and therapeutics ...
Monika Kumari   +16 more
doaj   +1 more source

IXA Biomedical Translation System at WMT16 Biomedical Translation Task [PDF]

open access: yesProceedings of the First Conference on Machine Translation: Volume 2, Shared Task Papers, 2016
In this paper we present the system developed at the IXA NLP Group of the University of the Basque Country for the Biomedical Translation Task in the First Conference on Machine Translation (WMT16). For the adaptation of a statistical machine translation system to the biomedical domain, we developed three approaches based on a baseline system for ...
Olatz Perez-de-Viñaspre, Gorka Labaka
openaire   +1 more source

Broadly neutralizing human antibodies against Omicron subvariants of SARS-CoV-2

open access: yesJournal of Biomedical Science, 2023
Background The COVID-19 pandemic continues to pose a significant worldwide threat to human health, as emerging SARS-CoV-2 Omicron variants exhibit resistance to therapeutic antibodies and the ability to evade vaccination-induced antibodies.
Hsiao-Ling Chiang   +5 more
doaj   +1 more source

Antibody cocktail effective against variants of SARS-CoV-2

open access: yesJournal of Biomedical Science, 2021
Background Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus with a high mutation rate.
Kang-Hao Liang   +10 more
doaj   +1 more source

A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants

open access: yesJournal of Biomedical Science, 2022
Background With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design that will provide broader neutralizing efficacy.
I-Jung Lee   +40 more
doaj   +1 more source

Broadly neutralizing antibodies against Omicron variants of SARS-CoV-2 derived from mRNA-lipid nanoparticle-immunized mice

open access: yesHeliyon, 2023
The COVID-19 pandemic continues to threaten human health worldwide as new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge. Currently, the predominant circulating strains around the world are Omicron variants, which can
Ruei-Min Lu   +11 more
doaj   +1 more source

Antibody CDR amino acids underlying the functionality of antibody repertoires in recognizing diverse protein antigens

open access: yesScientific Reports, 2022
Antibodies recognize protein antigens with exquisite specificity in a complex aqueous environment, where interfacial waters are an integral part of the antibody–protein complex interfaces.
Hung-Pin Peng   +8 more
doaj   +1 more source

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