Results 61 to 70 of about 421,156 (296)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Meaning Factory at SemEval-2017 Task 9: Producing AMRs with Neural Semantic Parsing [PDF]
, 2017 We evaluate a semantic parser based on a character-based sequence-to-sequence model in the context of the SemEval-2017 shared task on semantic parsing for AMRs.
Bos, Johan, van Noord, Rik
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Multilingual translation for zero-shot biomedical classification using BioTranslator
Nature Communications, 2023 Here, the authors develop the cross-modal translation method BioTranslator to translate the textual description to non-text biological data. This approach frees scientists from limiting their analysis within predefined controlled vocabularies.
Hanwen Xu +4 more
doaj +1 more source
A computational model for real-time calculation of electric field due to transcranial magnetic stimulation in clinics [PDF]
, 2015 The aim of this paper is to propose an approach for an accurate and fast (real-time) computation of the electric field induced inside the whole brain volume during a transcranial magnetic stimulation (TMS) procedure. The numerical solution implements the
Apollonio, Francesca +6 more
core +3 more sources
Categorizing biomedical research: the basics of translation
The FASEB Journal, 2017 ABSTRACT As biomedical research has evolved over the past century, the terminology employed to categorize it has failed to evolve in parallel to accommodate the implications of these changes. In particular, the terms basic research and translational research as used today in biomedicine seem especially problematic.
Jeffrey S, Flier, Joseph, Loscalzo
openaire +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Nanotechnologies for biomedical science and translational medicine [PDF]
Proceedings of the National Academy of Sciences, 2015 In 2000 the United States launched the National Nanotechnology Initiative and, along with it, a well-defined set of goals for nanomedicine. This Perspective looks back at the progress made toward those goals, within the context of the changing landscape in biomedicine that has occurred over the past 15 years, and considers advances that are likely to ...
openaire +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A Large Parallel Corpus of Full-Text Scientific Articles
, 2019 The Scielo database is an important source of scientific information in Latin America, containing articles from several research domains. A striking characteristic of Scielo is that many of its full-text contents are presented in more than one language ...
Becker, Karin +2 more
core +2 more sources