Results 41 to 50 of about 73,682 (231)
Journal of Applied Toxicology, EarlyView.ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro +5 more
wiley +1 more source
The effect of experience and of dots\u2019 density and duration on the detection of coherent motion in dogs [PDF]
, 2018 Knowledge about the mechanisms underlying canine vision is far from being exhaustive, especially that concerning post- retinal elaboration. One aspect that has received little attention is motion perception, and in spite of the common belief that dogs ...
Battaglini, Luca +5 more
core +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND Olive (Olea europaea L.) byproducts, such as seeds and leaves, are abundant agro‐industrial residues and represent underexplored protein sources with potential health relevance. However, the repertoire of bioactive peptides that may be released from olive proteins during gastrointestinal digestion remains poorly characterized.
Teresa Gonzalez‐de la Rosa +6 more
wiley +1 more source
Novel insights into the assembly of the yeast translation initiation multifactor complex: The critical role of eIF5. [PDF]
Protein SciAbstract The eukaryotic translation initiation is a biological process in which at least a dozen eukaryotic initiation factors (eIFs) are involved. Specifically, eIF3, eIF1, eIF5, and eIF2 as a ternary complex (eIF2‐TC) bound to GTP and methionyl initiator tRNA (Met‐tRNAiMet).
de la Fuente BS +6 more
europepmc +2 more sources
Complementary and Integrative Medicine for the Treatment of Tourette's Syndrome
Movement Disorders Clinical Practice, EarlyView.Abstract Background There is widespread interest in complementary and integrative medicine (CIM) among people with Tourette's syndrome (TS). Objective To perform a systematic review of evidence on the use of CIM to reduce tics and improve tic‐related quality of life.
Tamara Pringsheim +21 more
wiley +1 more source
REVISTA PRAXIS, 2018 Este artículo muestra que la justifcación del enfoque médico dominante, de que su actividad es científca porque parte de la evidencia de las pruebas, en muchos casos observacionales, es un acto de fe, que resulta completamente anacrónico en comparación con los debates científcos contemporáneos.
openaire +2 more sources
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2018 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
core +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Titanium dioxide (TiO2), used as a food additive (labeled E171 in Europe), was withdrawn from the European market in 2022. The E171 toxicity mechanism involves its uptake, oxidative stress, DNA damage, and inflammation. It has been hypothesized that the TiO2 accumulation nanoparticles (NPs) or E171 triggers tissue damage, and some studies have
Carmen Ximena Martínez‐Escutia +3 more
wiley +1 more source
The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB [PDF]
, 2017 Purpose: Cancer stem cells (CSC) are self-renewing tumor cells, with the ability to generate diverse differentiated tumor cell subpopulations. They differ from normal stem cells in the deregulation of the mechanisms that normally control stem cell ...
Carnero Moya, Amancio +4 more
core +1 more source
VIEW, EarlyView.Schematic representation of the microfluidic platform with its advantages. Abstract A major challenge in pharmacology is the limited selectivity of therapeutic compounds toward specific tissues or cells. Drugs often distribute systemically before reaching the intended site of action, affecting nontarget cells and potentially reducing efficacy or ...
Maria Testa +8 more
wiley +1 more source