Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells [PDF]
Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and gemcitabine, although resistance limits its clinical benefits.
Flores, M. Luz +7 more
core +1 more source
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez +6 more
wiley +1 more source
La ginecología natural en América Latina: Un movimiento sociocultural del presente
Este artículo se propone describir algunas de las características de la Ginecología Natural, a partir de la consideración de su desarrollo como expresión sociocultural emergente en la última década en América Latina.
Núria Calafell Sala
doaj
Efecto de una dosis de lidocaína y ketamina sobre el consumo intraoperatorio de opioides en pacientes sometidas a cirugía ginecológica electiva bajo anestesia general. Estudio piloto aleatorizado y controlado con placebo [PDF]
Background and goal of study: there is evidence that perioperative intravenous ketamine and lidocaine reduce postoperative pain, postoperative opioids consumption, shortens hospital stay and accelerates intestinal function recovery.
Vilches Arenas, Ángel
core
The nuclear receptor LXRα controls the functional specialization of splenic macrophages. [PDF]
Macrophages are professional phagocytic cells that orchestrate innate immune responses and have considerable phenotypic diversity at different anatomical locations. However, the mechanisms that control the heterogeneity of tissue macrophages are not well
A-Gonzalez, Noelia +19 more
core +1 more source
Disruption of Asparagine Synthetase Is Associated to Increased Biomass in Lotus japonicus
ABSTRACT Asparagine (Asn) constitutes the major form of nitrogen translocated within Lotus japonicus plants. In this work we use knock‐out (KO) LORE1 mutants‐deficient in the asparagine synthetase gene (LjASN1), which is the most highly expressed ASN gene in plants grown under non‐symbiotic (NS) conditions, but much less expressed under symbiotic (S ...
Sara Rosa‐Téllez +5 more
wiley +1 more source
Proceso Visionario hacia el Desarrollo Biotecnológico
El Centro de Investigación en Biotecnología (CIB), creado en 1994, es la unidad de investigación de la Escuela de Biología del Instituto Tecnológico de Costa Rica.
Elizabeth Arnáez-Serrano +5 more
doaj +1 more source
Fasentin, a glucose uptake inhibitor, is also able to inhibit angiogenesis [PDF]
Es comunicación a congreso en formato pósterThe role of glucose on endothelial cell (EC) metabolism and angiogenesis has been an emerging issue in the last few years.
Carrillo, Paloma +4 more
core
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido +6 more
wiley +1 more source
Abstract Membrane fusion between HIV and host cells requires interaction between the N‐terminal and C‐terminal repeat regions (NHR and CHR) of the gp41 envelope subunit. A deep hydrophobic pocket (HP) on the surface of NHR is considered crucial in this interaction.
Daniel Polo‐Megías +9 more
wiley +1 more source

