Synergistic Reduction of Breast Cancer Cell Viability and Aggressiveness Through Dual Inhibition of APE1 Redox Function and STAT3 Signaling. [PDF]
ABSTRACT Aggressiveness and resistance to treatments are significant problems in cancer management. In this scenario, searching for new pharmacological targets for therapies is essential. The APE1 redox domain coactivates transcription factors that favor cancer malignancy. One of APE1's targets, STAT3, coordinates the transcription of genes involved in
Rodrigues MMS +7 more
europepmc +2 more sources
The meniscal extrusion index is a reliable indirect sign of different meniscal lesion patterns: a classification based on percentage of meniscal extrusion. [PDF]
Abstract Purpose This study's goal is to propose a straightforward classification system based on the MEI (Meniscal Extrusion Index), a measure of meniscal extrusion, that relates to various meniscal lesion patterns and has clinical and biomechanical significance.
Compagnoni R +6 more
europepmc +2 more sources
A fast, easy and reliable method for hamstrings graft size prediction in anterior cruciate ligament reconstruction. [PDF]
Abstract Purpose The aim of this study is to describe and validate a simple and reliable method to pre‐operatively predict the size of the ACL graft in the double strand technique with autologous semitendinosus–gracilis tendons on the same MRI used for ACL rupture diagnosis.
Minoli C +8 more
europepmc +2 more sources
Mice population dynamics and structure over time and space after wildfires
Wood and Algerian mice live syntopically within burnt areas, the former species being more abundant. In this study, adult females were recaptured more often over time, while males were found to cover greater distances. We found that recovery strategies of Mediterranean rodents are mainly driven by ex situ immigration from unburnt areas.
R. Puig‐Gironès, P. Pons
wiley +1 more source
Lateral wedge insoles and their use in ankle instability
Abstract The aim of the present study is to assess the immediate effects of applying lateral wedge insoles of different heights (0.00, 0.3, 0.4, and 0.6 cm) in patients with chronic ankle instability (CAI) in normal and supinated feet during a Star Excursion Balance Test (SEBT) and in the reflex response of Peroneus Longus (PL), Peroneus Brevis (PB ...
Inés Palomo‐Fernández +5 more
wiley +1 more source
Benthic diatoms and some environmental conditions in three lowland streams [PDF]
This article reports on the ecological preferences of benthic diatoms in relation to pH, conductivity and organic pollution-eutrophication and their tolerance spectrums. Three Pampean streams subjected to different human impacts were studied.
Gomez, Nora, Licursi, Magdalena
core +2 more sources
En este artículo exponemos algunas mejoras y aportaciones en dos aspectos de los sistemas de gestión de aprendizaje (LMS). El primer aspecto es la seguridad y la autenticación, donde presentamos una modalidad de combinar la autenticación tradicional de ...
R. Gil +9 more
doaj +1 more source
Evaluation of Mesocyclops annulatus (Copepoda: Cyclopoidea) as a control agent of Aedes aegypti (Diptera: Culicidae) in Argentina. [PDF]
We evaluated the potential of Mesocyclops annulatus as a control agent of Aedes aegypti in La Plata city (Argentina). Mosquito larval survivorship due to predation by these copepods was estimated at weekly intervals during the oviposition period of A ...
Liljesthrom, Gerardo Gustavo +3 more
core +3 more sources
Evaluación del desarrollo testicular y medidas morfométricas en ovinos de pelo colombiano
Las medidas corporales en ovinos son útiles como indicador de tipo y función, permiten mejorar la selección. Se conocen estudios biométricos en ovinos que, relacionan la importancia de estas medidas con algunas variables productivas.
Amado Espitia-Pacheco +2 more
doaj +1 more source
Desenvolvimento de um protótipo de aplicativo para biometria fetal (Med Baby)
Objetivo: Relatar a experiência de desenvolvimento de um protótipo de aplicativo para análise da biometria fetal. Metodologia: Relato de experiência do desenvolvimento do protótipo de aplicativo MedBaby, entre outubro 2021 a janeiro de 2022.
Lorenna Paylla Moreira de Lima +2 more
doaj +1 more source

