Synergistic Reduction of Breast Cancer Cell Viability and Aggressiveness Through Dual Inhibition of APE1 Redox Function and STAT3 Signaling. [PDF]
ABSTRACT Aggressiveness and resistance to treatments are significant problems in cancer management. In this scenario, searching for new pharmacological targets for therapies is essential. The APE1 redox domain coactivates transcription factors that favor cancer malignancy. One of APE1's targets, STAT3, coordinates the transcription of genes involved in
Rodrigues MMS +7 more
europepmc +2 more sources
Paddy ponding water quality responses to land use intensity in flooded rice systems in Uruguay. [PDF]
Abstract Understanding water quality responses in flooded rice (Oryza sativa L.) systems is essential to reconcile high productivity with environmental protection. This study provides the first high‐frequency dataset of paddy water quality dynamics in temperate South American rice systems, conducted in the Laguna Merín Basin (Uruguay–Brazil).
Cantou G +3 more
europepmc +2 more sources
The meniscal extrusion index is a reliable indirect sign of different meniscal lesion patterns: a classification based on percentage of meniscal extrusion. [PDF]
Abstract Purpose This study's goal is to propose a straightforward classification system based on the MEI (Meniscal Extrusion Index), a measure of meniscal extrusion, that relates to various meniscal lesion patterns and has clinical and biomechanical significance.
Compagnoni R +6 more
europepmc +2 more sources
Abstract Purpose The aim of this study is to describe and validate a simple and reliable method to pre‐operatively predict the size of the ACL graft in the double strand technique with autologous semitendinosus–gracilis tendons on the same MRI used for ACL rupture diagnosis.
C. Minoli +8 more
wiley +1 more source
Mice population dynamics and structure over time and space after wildfires
Wood and Algerian mice live syntopically within burnt areas, the former species being more abundant. In this study, adult females were recaptured more often over time, while males were found to cover greater distances. We found that recovery strategies of Mediterranean rodents are mainly driven by ex situ immigration from unburnt areas.
R. Puig‐Gironès, P. Pons
wiley +1 more source
Selected Legal Aspects of Processing Employee Biometric Data
Given the growing popularity of biometrics, doubts about the conditions for biometric data processing can be noticed in practice. These inaccuracies take place in various areas of law, including labour law.
Sylwia Zaborska
doaj +1 more source
Morphology and biometry of the thymus gland in macaw of Ara and Anodorhynchus genera [PDF]
Foram utilizados 12 exemplares de Ara ararauna – seis fêmeas e seis machos –, cinco exemplares de Ara chloropterus (uma fêmea e quatro machos) e dois exemplares de Anodorhynchus hyacinthinus – uma fêmea e um macho –, todos adultos, doados por criadouro ...
Armando, A.P.R.N. +7 more
core +1 more source
Sistemas automáticos de impressões digitais integrando Java e Arduino
A biometria digital é a característica biométrica mais difundida e utilizada dentre as demais. Ela utiliza-se das variações das linhas existentes nas pontas dos dedos para determinar a identidade de um indivíduo.
Esequias Aquino Duarte Neto +4 more
doaj +1 more source
MORFOLOGIA DE FRUTOS E QUALIDADE FÍSICA E FISIOLÓGICA DE SEMENTES DE CULTIVARES DE JILOEIRO
Objetivou-se com este trabalho determinar aspectos morfológicos de frutos e da qualidade física e fisiológica de semente de cultivares de jiloeiro (SolanumgiloRaddi).
A. R. Martins +5 more
doaj +1 more source
In current clinical practice for breast cancer patients, estrogen (ER) and progesterone receptor (PgR) concentrations, quantified by the dextran-coated charcoal assay, are categorized by an arbitrary cutoff into a negative or positive status.
D. Coradini +7 more
doaj +1 more source

