Results 31 to 40 of about 3,762 (133)

A new model for parent-of-origin effect analyses applied to Brown Swiss cattle slaughterhouse data

Animal, 2017
Genomic imprinting is a phenomenon that arises when the expression of genes depends on the parental origin of alleles. Epigenetic mechanisms may induce the full or partial suppression of maternal or paternal alleles, thereby leading to different types of
I. Blunk, M. Mayer, H. Hamann, N. Reinsch   +3 more
doaj   +1 more source

Pulmonary Herpes Simplex Virus Reactivation in Invasively Mechanically Ventilated Patients With COVID‐19 in Intensive Care Unit

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Patients in intensive care units (ICU) under mechanical ventilation, particularly those with SARS‐CoV‐2 infection, are highly susceptible to Herpes simplex virus (HSV) reactivation. Given the lack of data on the SARS‐CoV‐2 Omicron and Delta variants, this study aimed to assess the prevalence of pulmonary HSV reactivation in mechanically ...
Bastien Zarlenga, Florent Wallet, Alexandre Gaymard, Anne‐Claire Lukaszewicz, Gregory Destras, Christophe Ginevra, Bruno Simon, Jennifer Giorgi, Muriel Rabilloud, Salomé Avenas, Alexis Trecourt, Geneviève Billaud, Florence Morfin, Jean‐Christophe Richard, Emilie Frobert   +14 more
wiley   +1 more source

Evaluating the current state of Mendelian randomization studies: a protocol for a systematic review on methodological and clinical aspects using neurodegenerative disorders as outcome

Systematic Reviews, 2018
Background Mendelian randomization (MR) is fast becoming a popular method to judge causality from routinely conducted observational studies. However, stringent underlying statistical assumptions, missing biological information, and high sample size ...
Sandeep Grover, Fabiola Del Greco M., Inke R. König   +2 more
doaj   +1 more source

The impact of deregressed foreign breeding values on national beef cattle single-step genomic evaluation

Genetics Selection Evolution
Background In recent years, genetic evaluations in cattle breeding have shifted from purely national evaluations to multinational evaluations considering relatives from other countries.
Damilola Adekale, Zengting Liu, Ross Evans, Thierry Pabiou, Reinhard Reents, Dierck Segelke, Jens Tetens   +6 more
doaj   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2682-2692, August 2026.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2834-2852, August 2026.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Buchbesprechung: S.-C. Chow: Controversial Statistical Issues in Clinical Trials

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2014
[english] The book of Chow gives an overview over many controversial aspects in conducting and analyzing of clinical trials. The author of this book review (translation of the ISCB Bulletin) concludes, that all parties involved in clinical trials should ...
Muche, Rainer
doaj   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, Volume 101, Issue 4, Page 1805-1829, August 2026.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source

Denning Phenology Mediates Sea‐Ice Loss Impacts on Early Reproductive Success in Polar Bears

Global Change Biology, Volume 32, Issue 8, August 2026.
Changes in overwinter sheltering phenology in response to climate change and their fitness consequences have rarely been studied. Here, we show that climate change has disrupted the phenology of overwinter maternity denning in polar bears, with females emerging from den earlier when sea‐ice had been scarce the preceding year.
Marwan Naciri, Jon Aars, Marlène Gamelon, Magnus Andersen, Andrew E. Derocher, Øystein Wiig, Sarah Cubaynes   +6 more
wiley   +1 more source

KI in der Schule und im interdisziplinären Studium – Regelbasierte Systeme und Wissensrepräsentation im Kontext von Agenten

Informatische Bildung in Schulen
Dieser Artikel befasst sich mit der didaktischen Aufbereitung ausgewählter Aspekte des Themenkomplexes der Wissensrepräsentation und der regelbasierten Systeme, die zu den klassischen Teilgebieten der künstlichen Intelligenz zählen.
Daan Apeldoorn, Andre Thevapalan
doaj   +1 more source