Results 11 to 20 of about 25,496 (284)

Innate Biomineralization [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
In vertebrates, biomineralization is a feature considered unique to mature osteoblasts and odontoblasts by which they synthesize hydroxyapatite (HAP), which is deposited in the collagen matrix to construct endoskeleton. For many decades, the mechanisms that modulate differentiation and maturation of these specialized cells have been sought as a key to ...
Tian, Erming   +3 more
openaire   +3 more sources

Green Approach in Synthesis of Bio-Inspired Materials

open access: yesCrystals, 2021
In this Special Issue, we focus on biomineralization/pathological biomineralization systems and the synthesis of bioinspired materials [...]
Anamarija Stanković   +3 more
doaj   +2 more sources

Biomineralization at fluid interfaces [PDF]

open access: yesAdvances in Colloid and Interface Science, 2020
Biomineralization is of paramount importance for life on Earth. The delicate balance of physicochemical interactions at the interface between organic and inorganic matter during all stages of biomineralization resembles an extremely high complexity. The coordination of this sophisticated biological machinery and physicochemical scenarios is certainly a
Cano, Manuel, Giner-Casares, Juan J.
openaire   +5 more sources

A Programmable Calcification Nanoplatform for Loco-Regional Calcification-Immune Hepatocellular Carcinoma Therapy. [PDF]

open access: yesAdv Sci (Weinh)
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Liu L   +11 more
europepmc   +2 more sources

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton. [PDF]

open access: yesAdv Sci (Weinh)
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Bourne LE   +15 more
europepmc   +2 more sources

Antioxidant Activity of Auricularia auricula Polysaccharides with Different Molecular Weights and Cytotoxicity Difference of Polysaccharides Regulated CaOx to HK-2 Cells

open access: yesBioinorganic Chemistry and Applications, 2023
Objective. This study aimed to investigate the growth of calcium oxalate (CaOx) crystals regulated by Auricularia auricular polysaccharides (AAPs) with different viscosity-average molecular weights (Mv), the toxicity of AAP-regulated CaOx crystals toward
Bao-Li Heng   +3 more
doaj   +1 more source

Sulfated Undaria pinnatifida Polysaccharide Promotes Endocytosis of Nano-Calcium Oxalate Dihydrate by Repairing Subcellular Organelles in HK-2 Cells

open access: yesAntioxidants, 2023
The clinical manifestation of primary hyperoxaluria includes hyperoxaluria and recurrent urinary calculi. In this study, an oxidative damage model was constructed based on oxalate damage to the human renal proximal tubular epithelial cells (HK-2), and a ...
Xue-Wu Chen   +2 more
doaj   +1 more source

A Bivalve Biomineralization Toolbox [PDF]

open access: yesMolecular Biology and Evolution, 2021
Abstract Mollusc shells are a result of the deposition of crystalline and amorphous calcite catalyzed by enzymes and shell matrix proteins (SMP). Developing a detailed understanding of bivalve mollusc biomineralization pathways is complicated not only by the multiplicity of shell forms and microstructures in this class, but also by the ...
Yarra, Tejaswi   +2 more
openaire   +4 more sources

Antioxidant Activities and Cytotoxicity of the Regulated Calcium Oxalate Crystals on HK-2 Cells of Polysaccharides from Gracilaria lemaneiformis with Different Molecular Weights

open access: yesFoods, 2023
The antioxidant activities of seven degraded products (GLPs) with different molecular weights (Mw) of polysaccharides from Gracilaria lemaneiformis were compared. The Mw of GLP1–GLP7 were 106, 49.6, 10.5, 6.14, 5.06, 3.71 and 2.42 kDa, respectively.
Jing-Hong Liu   +2 more
doaj   +1 more source

Carboxymethylated Rhizoma alismatis Polysaccharides Regulate Calcium Oxalate Crystals Growth and Reduce the Regulated Crystals’ Cytotoxicity

open access: yesBiomolecules, 2023
Objective: This study explored the effects of polysaccharides (RAPD) extracted from the traditional anti-stone Chinese medicine Rhizoma alismatis and their carboxymethylated derivatives (RAPs) on the crystal phase, morphology, and size of calcium oxalate
Xiao-Yan Cheng, Jian-Ming Ouyang
doaj   +1 more source

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