Results 51 to 60 of about 4,862 (159)

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva, Zhenze Jiang, Chenxi Liu, Pavla Fajtová, Thaiz R. Teixeira, Giovana de Castro Fiorini Maia, Lawrence J. Liu, Nelly El‐Sakkary, Danielle E. Skinner, Ali Syed, Steven C Wang, Conor R. Caffrey, Anthony J. O'Donoghue   +12 more
wiley   +1 more source

Freshwater snails and Schistosomiasis mansoni in the state of Rio de Janeiro, Brazil: IV - Sul Fluminense Mesoregion

Memorias do Instituto Oswaldo Cruz, 2004
In this paper, the forth of a series dealing with the survey of freshwater gastropods of the state of Rio de Janeiro, the results of collections carried out in the Sul Fluminense Mesoregion from 2000 to 2002 are presented and revealed the occurrence of ...
Silvana C Thiengo, Aline C Mattos, M Fernanda Boaventura, Monica A Fernandez   +3 more
doaj   +1 more source

Unexpected Shifts in Bivalve Function From Filtration to Transmission Risk

Freshwater Biology, Volume 70, Issue 6, June 2025.
ABSTRACT Understanding the complex interactions between filter‐feeding species and zoonotic disease transmission in aquatic environments is crucial for accurately quantifying the ecosystem services provided by these organisms. This study explores for the first time the roles of freshwater bivalves in the transmission dynamics of emerging zoonotic ...
Jakub Hradečný, Divakaran Pandian, Lucia Anettová, Anna Šipková, Juan Felipe Escobar‐Calderón, Mehrak Mohammadi, Kateřina Gregarová, David Modrý, Karel Douda   +8 more
wiley   +1 more source

Malacological survey of Biomphalaria snails in municipalities along the Estrada Real in the southeast of the State of Minas Gerais, Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: The increasing practice of ecotourism and rural tourism in the State of Minas Gerais, Brazil, highlights the importance of studies concerning the occurrence of potential intermediate hosts of Schistosoma mansoni.
Sandra Helena Cerrato Tibiriçá, Adalberto Mitterofhe, Milton Ferreira de Castro, Adilson da Costa Lima, Murilo Gonçalves, Izabella de Oliveira Pinheiro, Corina da Costa Freitas, Ricardo José Paula de Souza e Guimarães, Omar dos Santos Carvalho, Elaine Soares Coimbra   +9 more
doaj   +1 more source

Co‐endemicity of schistosomiasis and tegumentary leishmaniasis: Spatial co‐clustering in endemic areas

Tropical Medicine &International Health, Volume 30, Issue 6, Page 556-568, June 2025.
Abstract Objectives Schistosomiasis and tegumentary leishmaniasis simultaneously affect areas in tropical and subtropical regions. Co‐infected individuals show a less‐than‐optimal response to treatment and increased regulatory immune responses. However, no study has determined where Schistosoma–Leishmania co‐infections are more likely to occur ...
Genil Mororó Araújo Camelo, Jeferson Kelvin Alves de Oliveira Silva, Dharliton Soares Gomes, Laura Maggi, Stefan Michael Geiger, David Soeiro Barbosa, Deborah Aparecida Negrão‐Corrêa   +6 more
wiley   +1 more source

Morphological and molecular characterization of invasive Biomphalaria straminea in southern China

Infectious Diseases of Poverty, 2018
Background Schistosomiasis is a common parasitic disease designated as a neglected tropical disease by the World Health Organization. Schistosomiasis mansoni is a form of the disease that is caused by the digenean trematode Schistosoma mansoni ...
Mohamed R. Habib, Shan Lv, Yun-Hai Guo, Wen-Biao Gu, Claire J. Standley, Roberta L. Caldeira, Xiao-Nong Zhou   +6 more
doaj   +1 more source

Latex of "Coroa de Cristo" (Euphorbia Splendens): an effective molluscicide

Memorias do Instituto Oswaldo Cruz, 1986
An aqueous solution of the latex of "coroa de cristo" (Euphorbia splendens var. hislopii) showed molluscicide action (LD90) at a concentration lower than 0.5 ppm on Biomphalaria glabrata and B.
Maurício C. de Vasconcelos, Virgínia T. Schall   +1 more
doaj   +1 more source

[Competitive behavior of Biomphalaria glabrata and Biomphalaria tenagophila--laboratory studies].

Memorias do Instituto Oswaldo Cruz, 1990
Observation about cohabitation among B. glabrata and B. tenagophila revealed a greater vulnerability of B. tenagophila population during the process of competition when its density was severely decreased in 12 trials, moderate in 2 trials. It was higher than B. glabrata in only one trial.
M B, dos Santos, J R, de Freitas, E de S, Alves, L A, Rocha   +3 more
openaire   +1 more source

Comparação da capacidade ovipositora de Biomphalaria glabrata (Say, 1818), Biomphalaria tenagophila (D'Orbigni, 1835) e Biomphalaria straminea (Dunker, 1848), mantidas em laboratório [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 1978
O autor comparou a capacidade ovipositora de 3 espécies de Planorbidae, Biomphalaria glabrata, B. tenagophila e B. straminea, durante um período de 30 dias, compreendidos entre os meses de Março e Abril de 1978. Registrou-se diariamente o número de ovos e desovas, referentes a 20 exemplares de cada espécie em questão.
openaire   +5 more sources

Contribuição ao estudo da biologia de Biomphalaria occidentalis Paraense, 1981 e de Biomphalaria tenagophila (d'Orbigny, 1835), em condições de laboratório

Revista de Saúde Pública
Com o objetivo de comparar a duração do período embrionário, a fecundidade e a fertilidade de Biomphalaria occidentalis Paraense, 1981 com a de B, tenagophila (d'Orbigny, 1835), exemplares de ambas as espécies foram criados em aquários dotados das mesmas
Maísa Rose Domenico Elmor, Jorge Faria Vaz, Léa Maria Cappelletti Gonçalves   +2 more
doaj