Results 61 to 70 of about 23,573 (240)

BgTEP: An Antiprotease Involved in Innate Immune Sensing in Biomphalaria glabrata

bioRxiv, 2018
Insect Thioester-containing protein (iTEP) is the most recently defined group among the TEP superfamily. TEPs are key components of the immune system, and iTEPs from flies and mosquitoes were shown to be major immune weapons. Initially characterised from
Anaïs Portet, R. Galinier, Silvain Pinaud, Julien Portela, Fanny C. Nowacki, B. Gourbal, D. Duval   +6 more
semanticscholar   +1 more source

Molluscicidal activity of Persea americana Mill. (Lauraceae) stem bark ethanolic extract against the snail Biomphalaria glabrata (Say, 1818): a novel plant-derived molluscicide?

Anais da Academia Brasileira de Ciências, 2020
Plant-derived molluscicides have been indicated as biodegradable and low-cost strategies for control of Biomphalaria spp., intermediate host for the Schistosoma.
Yasmim R R Silva, L. D. Silva, T. L. Rocha, D. B. Santos, J. Bezerra, K. B. Machado, J. A. M. Paula, V. C. S. Amaral   +7 more
semanticscholar   +1 more source

CRISPR/Cas9 Knockout of Shell Matrix Protein 1 in the Slipper‐Snail Crepidula atrasolea

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 5, Page 266-283, July 2025.
Methods for CRISPR/Cas9 shell matrix protein knockout in the snail, Crepidula atrasolea including optimizing RNP delivery and embryo husbandry, to the use of Sanger and MiSeq sequencing, and high‐content screening of embryos to characterize the loss of Shell Matrix Protein 1 (SMP1) during larval shell development.
Grant Batzel, Yiqun Wang, Antonia Bock, Elbereth Chen, Stephanie Neal, Rebecca N. Lopez‐Anido, Yoon Lee, Evan Tjeerdema, Emily Ignatoff, Tejasvi Patil, Gabriela Ramirez, Maryna P. Lesoway, Amro Hamdoun, Deirdre C. Lyons   +13 more
wiley   +1 more source

A Benzoic Acid Derivative and Flavokawains from Piper species as Schistosomiasis Vector Controls

Molecules, 2014
The search of alternative compounds to control tropical diseases such as schistosomiasis has pointed to secondary metabolites derived from natural sources.
Ludmila N. Rapado, Giovana C. Freitas, Adriano Polpo, Maritza Rojas-Cardozo, Javier V. Rincón, Marcus T. Scotti, Massuo J. Kato, Eliana Nakano, Lydia F. Yamaguchi   +8 more
doaj   +1 more source

Proteomic analysis of Biomphalaria glabrata plasma proteins with binding affinity to those expressed by early developing larval Schistosoma mansoni

PLoS Pathogens, 2017
Interactions between early developing Schistosoma mansoni larval stages and the hemolymph of its snail intermediate host represent the first molecular encounter with the snail’s immune system.
Xiao-jun Wu, N. Dinguirard, G. Sabat, H. Lui, Laura A. Gonzalez, M. Gehring, Utibe Bickham-Wright, T. Yoshino   +7 more
semanticscholar   +1 more source

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva, Zhenze Jiang, Chenxi Liu, Pavla Fajtová, Thaiz R. Teixeira, Giovana de Castro Fiorini Maia, Lawrence J. Liu, Nelly El‐Sakkary, Danielle E. Skinner, Ali Syed, Steven C Wang, Conor R. Caffrey, Anthony J. O'Donoghue   +12 more
wiley   +1 more source

Resistência de Biomphalaria schrammi de Arcos, Minas Gerais, Brasil, à infecção com duas cepas de schistosoma mansoni Resistence of Biomphalaria schrami of Arcos, Minas Gerais, Brazil, to infection with 2 strains of schistosomo mansoni

Memorias do Instituto Oswaldo Cruz, 1985
Descendentes do plonorbídeo Biomphalaria schrammi Crosse, 1864, coletados na localidade de Calciolândia, município de Arcos, Minas Gerais, Brasil foram expostos a miracídios de duas cepas de Schistosoma mansoni:"LE" de Belo Horizonte, Minas Gerais e "SJ"
Cecília Pereira de Souza, Carlos Tito Guimarães, Neusa Araújo, Carlos Rubens Teixeira da Silva   +3 more
doaj   +1 more source

The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni

PLoS Neglected Tropical Diseases, 2017
Background The debilitating human disease schistosomiasis is caused by infection with schistosome parasites that maintain a complex lifecycle alternating between definitive (human) and intermediate (snail) hosts.
Kathrin K. Geyer, U. Niazi, D. Duval, C. Cosseau, Chad Tomlinson, Iain W. Chalmers, M. Swain, David Cutress, Utibe Bickham-Wright, Sabrina E Munshi, C. Grunau, T. Yoshino, K. Hoffmann   +12 more
semanticscholar   +1 more source

Glabralysins, Potential New β-Pore-Forming Toxin Family Members from the Schistosomiasis Vector Snail Biomphalaria glabrata

Genes, 2020
Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive.
D. Lassalle, G. Tetreau, Silvain Pinaud, R. Galinier, N. Crickmore, B. Gourbal, D. Duval   +6 more
semanticscholar   +1 more source

Unexpected Shifts in Bivalve Function From Filtration to Transmission Risk

Freshwater Biology, Volume 70, Issue 6, June 2025.
ABSTRACT Understanding the complex interactions between filter‐feeding species and zoonotic disease transmission in aquatic environments is crucial for accurately quantifying the ecosystem services provided by these organisms. This study explores for the first time the roles of freshwater bivalves in the transmission dynamics of emerging zoonotic ...
Jakub Hradečný, Divakaran Pandian, Lucia Anettová, Anna Šipková, Juan Felipe Escobar‐Calderón, Mehrak Mohammadi, Kateřina Gregarová, David Modrý, Karel Douda   +8 more
wiley   +1 more source