Results 121 to 130 of about 70,680 (286)

Simple and High-Throughput Quantification of Mono- and Bivalent Foot-and-Mouth Disease Virus Vaccine Antigens by Differential Scanning Fluorimetry

Vaccines
Background/Objectives: An accurate quantification of the effective antigens from different serotypes is essential for the quality control of multivalent vaccines, but it remains challenging.
Yanli Yang, Xiaojie Chen, Ming Li, Fei Xin, Yi Zhao, Chengfeng Zhang, Yiping Pan, Chuanyu He, Sun He   +8 more
doaj   +1 more source

Practical considerations for optimal designs in clinical dose finding studies [PDF]

Determining an adequate dose level for a drug and, more broadly, characterizing its dose response relationship, are key objectives in the clinical development of any medicinal drug. If the dose is set too high, safety and tolerability problems are likely
Bretz, Frank, Dette, Holger, Pinheiro, José   +2 more
core  

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

BMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu, Nan Xu, Xin Li, Xiaowo Kang, Tieyuan Bian, Junsheng Lin, Hao Tang, Yinyin Bao, Lu Zhang, Hongyan Yuan, Mingxi Yao, Xingyu Jiang, Zhi Luo   +12 more
wiley   +1 more source

A questionnaire-based study on industrial waste management in Indian biopharmaceutical industries

Environment Conservation Journal
This study investigates industrial waste management practices within the Indian biopharmaceutical sector through a questionnaire-based approach. The questionnaire, distributed among ten Indian biopharmaceutical industries (Himachal Pradesh (30°57'26.3"
Ishika Pringle, Navjeevan Dadwal, Arun Kumar   +2 more
doaj   +1 more source

Prompting Fab Yeast Surface Display Efficiency by ER Retention and Molecular Chaperon Co-expression. [PDF]

, 2019
For antibody discovery and engineering, yeast surface display (YSD) of antigen-binding fragments (Fabs) and coupled fluorescence activated cell sorting (FACS) provide intact paratopic conformations and quantitative analysis at the monoclonal level, and ...
Ge, Xin, Iverson, Brent L, Lee, Ki Baek, Li, Junhong, Mei, Meng, Wang, Shengchen, Yi, Li, Zhang, Guimin   +7 more
core  

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Product and process development compliance in the Indian biopharmaceutical industry: Challenges and innovations

Environment Conservation Journal
This study explored product and process development in the Indian biopharmaceutical industries, crucial in developing, manufacturing, and distributing biopharmaceutical products.
Shivangi Uppal, Navjeevan Dadwal
doaj   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

Business Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko, Lauren Durivault, Meisam Ranjbari, Zahra Shams Esfandabadi, Bernard Yannou, Robert Heidsieck, Michael Saidani, Ghada Bouillass   +7 more
wiley   +1 more source

Research Strategies in Science-based Start-ups - Effects on performance in Danish and Swedish biotechnology [PDF]

Although biotech start-ups fail or succeed based on their research few attempts have been made to examine if and how they strategize in this core of their activity.
Finn Valentin, Henrich Dahlgren, Rasmus Lund Jensen   +2 more
core