Results 131 to 140 of about 98,340 (384)
NAFLD‐related hepatocellular carcinoma: The growing challenge
Hepatology, EarlyView., 2022 Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah +2 more
wiley +1 more source
HortScienceApigenin, an anticancer secondary metabolite, is produced in selected organs of a few plant taxa, including chamomile (Matricaria chamomilla) flowers and parsley (Petroselinum crispum) leaves. In this study, two cultivars of chamomile (Bodegold and Zloty
Rebekah C.I. Maynard +4 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims In the context of pharmacology and toxicology education, there is a growing shift toward programmatic assessment models that prioritize longitudinal learning, reflection and development of higher‐order cognitive skills. As part of this transition, we are exploring alternative and more meaningful forms of assessment. This qualitative study
Narin Akrawi +2 more
wiley +1 more source
Hepatology, EarlyView., 2022 Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens +8 more
wiley +1 more source
MULTISCALAR CLUSTERS AND NETWORKS AS THE FOUNDATIONS OF INNOVATION DYNAMICS IN THE BIOPHARMACEUTICAL INDUSTRY [PDF]
Based on the case of the biopharmaceutical industry, the aim of this paper is to challenge the core conviction now widespread within the “spatial clustering theory”, which devotes a key (if not exclusive) role to geographical proximity in explaining ...
Abdelillah HAMDOUCH, Marc-Hubert DEPRET
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Therapeutic drug monitoring education: The current state
British Journal of Clinical Pharmacology, EarlyView.Aims To evaluate available information on therapeutic drug monitoring (TDM) education programmes and their implementation across different countries. Methods The study was performed in two phases. First, a scoping review of scientific literature on available education programmes was performed.
Guenka Petrova +10 more
wiley +1 more source
The other GMP: good manufacturing practice and its importance in the validation of constructed pharmaceutical facilities [PDF]
, 2005 The work reported is part of an ongoing PhD study prompted by the particular difficulties encountered when two very different quality cultures interact (in this case Pharmaceutical industry clients and Construction industry providers).
Edge, Jerry +2 more
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Significance of Biopharmaceutics for Clinical Effectiveness of Drug Products [PDF]
, 1967 Don E. Francke
openalex +1 more source
AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma
British Journal of Clinical Pharmacology, EarlyView.Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl +11 more
wiley +1 more source