Results 261 to 270 of about 98,962 (385)

Using generalized quantitative structure–property relationship (QSPR) models to predict host cell protein retention in ion‐exchange chromatography

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis, Olivier Le Bussy, Geoffroy Geldhof, Marieke E Klijn, Marcel Ottens   +4 more
wiley   +1 more source

Formulation Strategies for Ezetimibe and Its Combinations: Advancing Biopharmaceutical and Therapeutic Potential. [PDF]

Drug Des Devel Ther
Priani SE, Chaerunisaa AY, Wilar G, Sopyan I.   +3 more
europepmc   +1 more source

Prescriptions for Excellence in Health Care Winter 2011 Dowload Full PDF [PDF]

, 2012

core   +1 more source

Delivering a new generation of potential biopharmaceutical blockbusters: Ultrasonic process engineering of plasmid DNA [PDF]

, 2008

openalex   +1 more source

Implementation and relevance of FAIR data principles in biopharmaceutical R&D.

Drug Discovery Today, 2019
J. Wise, Alexandra Grebe de Barron, A. Splendiani, B. Balali-Mood, Drashtti Vasant, E. Little, Gaspare Mellino, Ian Harrow, Ian Smith, Jan Taubert, K. van Bochove, M. Romacker, P. Walgemoed, R. Jiménez, R. Winnenburg, Tom Plasterer, V. Gupta, Victoria Hedley   +17 more
semanticscholar   +1 more source

Optimizing rapeseed protein purification: a continuous chromatographic approach for napin and cruciferin

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Napin and cruciferin, the predominant storage proteins in Brassica napus (rapeseed), exhibit favorable techno‐functional properties such as emulsification and gel formation, positioning them as promising candidates for the encapsulation and delivery of bioactive compounds. Their classification as GRAS (Generally Recognized As Safe),
Jonas Arnecke, Jessica Gillmann, Tim Börner, Mathias Hafner, Christian Frech   +4 more
wiley   +1 more source

Unicorns transforming the practice of urology: value creation and allocation in the digital age. [PDF]

World J Urol
Erben P, Rodler S, Turki AT, Witzsch U, Thielscher C.   +4 more
europepmc   +1 more source

Classification of Loratadine Based on the Biopharmaceutics Drug Classification Concept and Possible in Vitro-in Vivo Correlation

, 2004
M. Z. I. Khan, Dragica Raušl, Ružica Zanoški, Snježana Zidar, Jasna Horvat Mikulčić, Lara Krizmanić, Mirela Eskinja, Boris Mildner, Zdravka Knežević   +8 more
openalex   +2 more sources

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich, Rita Steigmiller, Viktor Simaev, Romas Skudas, Michael Schulte, Mathias Hafner, Christian Frech   +6 more
wiley   +1 more source

High-throughput glycosylation screening method for biologics development using MALDI-TOF-MS. [PDF]

Commun Chem
Zhang W, Xie L, Zhao H, Ma X, Ren S.
europepmc   +1 more source