Results 281 to 290 of about 98,962 (385)

Autoencoding Raman Spectra to Predict Analyte Concentrations

Journal of Raman Spectroscopy, EarlyView.
An autoencoder‐based machine learning regression model was developed using datasets from nuclear and biopharmaceutical industries, utilising spatial heterodyne spectrometers under spontaneous and resonance conditions. This study focuses on the impact of small data volumes on data augmentation and architecture designs.
Alex Poppe, Charles Warren, William Brooks, Stuart Gibson, Michael Foster   +4 more
wiley   +1 more source

Long Noncoding RNA TOB1‐AS1 Represses Cervical Cancer Cell Proliferation, Invasion, and Migration via the MicroRNA‐27a‐3p/Thioredoxin‐Interacting Protein Molecular Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cervical cancer (CC) remains a major global health concern, particularly due to its aggressive nature and limited treatment options in advanced stages. Long noncoding RNA (lncRNA) TOB1‐AS1 has been proposed as a tumor suppressor, yet its regulatory mechanism in CC remains unclear.
Yang Wang, You‐Xiang Hou, Li Xie, Yi‐La Xia, Yi‐Na Wang   +4 more
wiley   +1 more source

Comment on “Reference Intervals of Hematological Parameters Among Healthy Adults in Northern Sudan: A Community‐Based Cross‐Sectional Study”

Journal of Clinical Laboratory Analysis, EarlyView.
Rachana Mehta, Ranjana Sah
wiley   +1 more source

NAD+ Enhanced on Hearing Recovery in Sudden Sensorineural Hearing Loss: Randomized Controlled Trial

The Laryngoscope, EarlyView.
This 2‐year, single‐center, double‐blind study with a small sample size compared NAD+ and control groups in a randomized controlled trial for sudden sensorineural hearing loss (SSNHL). Results showed that NAD+ led to better hearing improvement from 7 days to 3 months and a shorter average recovery time compared to the control group.
Minqian Gao, Yingting Guan, Xuejing Yue, Hao Bao, Qianwen Li, Yiqing Zheng, Yongkang Ou, Haidi Yang   +7 more
wiley   +1 more source

Impact of Formulation Ingredient Compatibility on Encapsulation of Hydrophobic Substances in Polymeric Nanocarriers Prepared by Nanoprecipitation

Macromolecular Materials and Engineering, EarlyView.
Encapsulation of hydrophobic drugs in poly(lactic‐co‐glycolic) acid (PLGA) nanoparticles strongly depends on solvent and polymer compatibility. By linking Hansen solubility parameters with atomic force microscopy (AFM), scanning electron microscopy (SEM), and differential scanning calorimetry (DSC) analyses, the work reveals predictive markers of ...
Mark Sabura, Agnes‐Valencia Weiss, Svenja Pohl, Guido Kickelbick, Marc Schneider   +4 more
wiley   +1 more source

Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character

Macromolecular Rapid Communications, EarlyView.
Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz, Cevin P. Braksch, Jonas De Breuck, Matthias Hartlieb, Meike N. Leiske   +4 more
wiley   +1 more source

High Genetic Diagnostic Yield for Patients with Rare Movement Disorders at a Single‐Center Neurogenetics Clinic

Movement Disorders Clinical Practice, EarlyView.
Abstract Background As advanced molecular testing is incorporated into routine clinical practice, accessibility and yield remain limited. Objectives We propose a simplified and effective workup strategy to maximize diagnostic yield based on presented diagnostic yield of rare movement disorders at a tertiary Neurogenetics Clinic.
Dvir Penn, Yam Amir, Gil Ben David, Alina Kurolap, Dalit Barel, Uri Hamiel, Michal Bach, Emil Elhanan, Tali Barkan, Daphna Marom, Adi Mory, Noga Simantov, Gadi Maayan Eshed, Achinoam Faust‐Socher, Vered Livneh, Avner Thaler, Nurit Omer, Tamara Shiner, Nir Giladi, Tanya Gurevich, Hagit Baris Feldman, Roy N. Alcalay, Yuval Yaron, Penina Ponger   +23 more
wiley   +1 more source

Solidification to improve the biopharmaceutical performance of SEDDS: Opportunities and challenges.

Advanced Drug Delivery Reviews, 2019
P. Joyce, Tahnee J Dening, Tahlia R. Meola, H. B. Schultz, R. Holm, Nicky Thomas, C. Prestidge   +6 more
semanticscholar   +1 more source

Cell bank system, establishment, and application in the virus research, diagnosis, and biopharmaceutical industries. [PDF]

Biotechnol Notes
Soleimani S, Ghorani M.
europepmc   +1 more source

Rare but Relevant? Assessing Variants in Dystonia‐Linked Genes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Dystonia and Parkinson's disease (PD) exhibit clinical and genetic overlap, but the relevance of dystonia gene variants in PD remains unclear. Objective The aim was to assess the frequency of dystonia‐linked pathogenic variants in PD.
Lara M. Lange, Zih‐Hua Fang, Laurel Screven, Ai Huey Tan, Roy N. Alcalay, Rim Amouri, Roberta Bovenzi, Matilda Fenn, Joshua L.I. Frost, Joseph Jankovic, Simona Jasaityte, Zane Jaunmuktane, Beomseok Jeon, Ignacio Juan Keller Sarmiento, Rejko Krüger, Gregor Kuhlenbäumer, Chin‐Hsien Lin, Lukas Pavelka, Maria Teresa Periñan, Samia Ben Sassi, Tommaso Schirinzi, Jung Hwan Shin, Joshua M. Shulman, Yi Wen Tay, Ryan Uitti, Tom Warner, Zbigniew K. Wszolek, Lesley Wu, Ruey‐Meei Wu, Kirsten E. Zeuner, Cornelis Blauwendraat, Andrew Singleton, Niccolò E. Mencacci, Huw R. Morris, Shen‐Yang Lim, Katja Lohmann, Christine Klein, the Global Parkinson's Genetics Program (GP2)   +37 more
wiley   +1 more source