Results 291 to 300 of about 98,962 (385)

Bayesian hierarchical model predicts biopharmaceutical stability indicators and shelf life with application to multivalent human papillomavirus vaccine. [PDF]

Sci Rep
Ferrari F, Berger J, Lemieux L, Paduraru C, Dillon M, Liaw A, Carrillo R, Wong S, Salami H, Avalle P, Sherer E, Richardson D, Skomski D.   +12 more
europepmc   +1 more source

Money for nothing? Risks in biopharmaceutical companies from the perspective of public financiers

, 2008
Laura Heinonen, Birgitta Sandberg
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Bayesian Hierarchical Modeling for Variance Estimation in Biopharmaceutical Processes. [PDF]

Bioengineering (Basel)
Schach S, Eilert T, Presser B, Kunzelmann M.   +3 more
europepmc   +1 more source

Licensing exchange: Insights from the biopharmaceutical industry. [PDF]

Dutta, S., Wuyts, S.H.K.
core   +1 more source

Safety assessment of biopharmaceuticals: Japanese perspective on ICH S6 guideline maintenance

, 2008
Takahiro Nakazawa, Misao Kurokawa, Kazuya Kimura, Akihiro Wakata, Shigeru Hisada, Tadashi Inoue, Fumio Sagami, Shawn M. Heidel, Koji Kawakami, Kazutoshi Shinoda, Hiroshi Onodera, Yuji Kumagai, Yasuo Ohno, Nobuyuki Kawamura, T. Yamazaki, Tohru Inoue   +15 more
openalex   +2 more sources

Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration

ChemistryOpen, EarlyView.
Incorporating deep eutectic solvents into polymer‐based drug delivery systems (DDS) offers a sustainable route to enhance solubility, modify drug release, and create dual‐function carriers. This review explores how DES influence polymer structures and DDS performance, highlighting future prospects in personalized, responsive pharmaceutical technologies.
Nining Nining, Yoga Windhu Wardhana, Taofik Rusdiana, Hariyanti Hariyanti   +3 more
wiley   +1 more source

Development and characterization of gelatin microgel-stabilized silver nanoparticles loaded with curcumin: Evaluation of antibacterial, antioxidant, and antiproliferative activities. [PDF]

Sci Prog
Nguyen TLN, Nguyen NH, Sai CD, Bui Thi VH, Do HQ, Vu TT, Vu DM.   +6 more
europepmc   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Study Protocol of Expanded Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro-EXP) (Endocrinol Metab 2025;40:236-46, Jae Hoon Moon et al.). [PDF]

Endocrinol Metab (Seoul)
Lee EK, Moon JH, Park YJ.
europepmc   +1 more source