Novel tetravalent bispecific antibody, PSMA/TRAIL‑R2 REGULGENT™, induces selective tumor cell apoptosis without hepatotoxicity. [PDF]
Nakayama M +6 more
europepmc +1 more source
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen +7 more
wiley +1 more source
Assessment of Pharmacokinetics and Safety with Bioequivalence of the Nitroglycerin Sublingual Tablets of Two Formulations in Chinese Healthy Subjects: A Bioequivalence Study. [PDF]
Fu Q +10 more
europepmc +1 more source
Scalable Purification of Iron Oxide Nanoparticles for Organ Cryopreservation and Transplantation
Scalable purification of silica‐coated iron oxide nanoparticles (sIONP) enables organ‐scale nanowarming and cryopreservation. Tangential flow filtration (TFF) offers a rapid and scalable alternative to conventional ultracentrifugation, completing purification in 2.5 h.
Onyinyechukwu Justina Oziri +10 more
wiley +1 more source
Regulating the AI-enabled ecosystem for human therapeutics. [PDF]
Singh R, Paxton M, Auclair J.
europepmc +1 more source
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira +9 more
wiley +1 more source
Correction: Assessment of two methods for detecting carious dentin: an in vitro study. [PDF]
White J +9 more
europepmc +1 more source
Decellularized stem cell spheroids are limited by inefficient detergent penetration and biomolecule loss. A strategy using polydopamine‐coated nanofibers within hADSC spheroids enables efficient DNA removal while preserving extracellular matrix proteins.
Seung Jae Huh +7 more
wiley +1 more source
Does the impact of open innovation depend on contextual factors? A case of the Korean biopharmaceutical industry. [PDF]
Wang H, Song C, Shin K.
europepmc +1 more source
Analytical ultracentrifugation (AUC) is a powerful tool for studying the size–property relationships of nanomaterials in their native environment. A methodology based on AUC with in‐line multiwavelength emission detection is developed, enabling the measurement of the size‐resolved emission spectra of giant‐shell CdSe/CdS quantum dots.
Lisa M. S. Stiegler +5 more
wiley +1 more source

