Results 51 to 60 of about 98,340 (384)
Molecules, 2021 This study aimed to design an effective nanoparticle-based carrier for the oral delivery of fisetin (FST) with improved biopharmaceutical properties. FST-loaded nanoparticles were prepared with polyvinyl alcohol (PVA) and poly(lactic-co-glycolic acid ...
Wan-Yi Liu +3 more
semanticscholar +1 more source
Assessing the Immunogenicity of Biopharmaceuticals [PDF]
BioDrugs, 2016 Biopharmaceuticals have the potential to raise an immunogenic response in treated individuals, which may impact the efficacy and safety profile of these drugs. As a result, it is essential to evaluate immunogenicity throughout the different phases of the clinical development of a biopharmaceutical, including post-marketing surveillance.
Carlos Pineda +4 more
openaire +2 more sources
The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange
Antibodies, 2019 The usefulness of higher-order structural information provided by hydrogen/deuterium exchange-mass spectrometry (H/DX-MS) for the structural impact analyses of chemical and post-translational antibody modifications has been demonstrated in various ...
Felix Kuhne +9 more
doaj +1 more source
Polyphosphazenes for the delivery of biopharmaceuticals [PDF]
Journal of Applied Polymer Science, 2019 ABSTRACTPolyphosphazenes (PPZs) are a relatively new family of polymers based on a nitrogen–phosphorous backbone where organic side groups can be grafted. The synthetic route to PPZs is highly versatile such that it is possible to add many different functionalities that change completely the physicochemical and biological properties of the polymers ...
Wei-Hsin Hsu +4 more
openaire +3 more sources
Separations, 2018 Antibody-drug conjugates (ADCs) are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer.
Filip S. Ekholm +8 more
doaj +1 more source
Frontiers in Plant Science, 2022 Glycoproteins are the dominant category among approved biopharmaceuticals, indicating their importance as therapeutic proteins. Glycoproteins are decorated with carbohydrate structures (or glycans) in a process called glycosylation.
Alex van der Kaaij +4 more
doaj +1 more source
Digital Twins in Pharmaceutical and Biopharmaceutical Manufacturing: A Literature Review
Processes, 2020 The development and application of emerging technologies of Industry 4.0 enable the realization of digital twins (DT), which facilitates the transformation of the manufacturing sector to a more agile and intelligent one.
Yingjie Chen +5 more
semanticscholar +1 more source
Journal of Law, Medicine & Ethics, 2021 Enhancing research and development and ensuring equitable pricing and access to cutting-edge treatments are both vital to a biopharmaceutical innovation system that works in the public interest.
M. Mazzucato, Henry Lishi Li
semanticscholar +1 more source
Biotechnology Journal, 2006 AbstractThe biopharmaceutical industry, whose products are produced mainly by recombinant DNA technology, antibody technologies and cytotechnology, is the most important sector in industrial biotechnology, and is one of the most rapidly growing high‐tech industries.
Xianwen Hu, Shuyong Zhang, Qingjun Ma
openaire +4 more sources
Plant Molecular Farming: A Viable Platform for Recombinant Biopharmaceutical Production
Plants, 2020 The demand for recombinant proteins in terms of quality, quantity, and diversity is increasing steadily, which is attracting global attention for the development of new recombinant protein production technologies and the engineering of conventional ...
B. Shanmugaraj +2 more
semanticscholar +1 more source