Results 61 to 70 of about 47,170 (292)
Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice
Advanced Science, EarlyView.CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu +8 more
wiley +1 more source
Ten-Year Review and Outlook on the Innovation-Driven Development of China's Pharmaceutical Industry [PDF]
中国工程科学As a fundamental and strategic industry that safeguards people’s life and health, the pharmaceutical industry plays an irreplaceable role in building a strong public health security barrier, enhancing the core competitiveness of national industries, and ...
Song Li +5 more
doaj +1 more source
Production planning of biopharmaceutical manufacture. [PDF]
, 2006 Multiproduct manufacturing facilities running on a campaign basis are increasingly becoming the norm for biopharmaceuticals, owing to high risks of clinical failure, regulatory pressures and the increasing number of therapeutics in clinical evaluation ...
Lakhdar, K.
core
Scheduling Challenges in Biopharmaceutical Manufacturing
, 2007 Δημοσιεύσεις μελών--ΣΤΕΤ-Δ--Τμήμα Τεχνολογίας Τροφίμων--2007For a scheduling tool to be acceptable and effective in biopharmaceutical manufacturing it must embrace the richness of constraints that exist in the biomanufacturing floor. It must also provide
Koulouris, Alexandros +5 more
core +1 more source
Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria
Advanced Science, EarlyView.A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng +8 more
wiley +1 more source
Locust bean gum: exploring its potential for biopharmaceutical applications [PDF]
, 2012 Polysaccharides have been finding, in the last decades, very interesting and useful applications in the biomedical and, specifically, in the biopharmaceutical field.
Dionísio, Marita +3 more
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui +12 more
wiley +1 more source
Evaluation of pancreatin stability through enzyme activity determination
Acta Pharmaceutica, 2016 Pancreatin is a biotechnological product containing an enzyme complex, obtained from porcine pancreas, that is employed in treating pancreatic diseases.
Terra Gleysson De Paula +3 more
doaj +1 more source
Risk Management in Biopharmaceutical Supply Chains [PDF]
, 2011 Biopharmaceutical supply chains present considerable complexity issue for the formulation of optimal plans due to significant uncertainty in the supply chain.
Ma, Yao
core
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu +9 more
wiley +1 more source